MedStar Authors catalog › Details for: Role of invasive imaging in acute and long-term assessment of bioresorbable scaffold technology.
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Role of invasive imaging in acute and long-term assessment of bioresorbable scaffold technology.

by Garcia-Garcia, Hector M.
Citation: Catheterization & Cardiovascular Interventions. 88(S1):38-53, 2016 Nov.Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.Published: 2016ISSN: 1522-1946.Full author list: Chamie D; Garcia-Garcia H; Costa RA; Onuma Y; Abizaid A; Serruys PW.UI/PMID: 27797463.Subject(s): *Absorbable Implants | *Coronary Artery Disease/di [Diagnosis] | Coronary Artery Disease/su [Surgery] | *Diagnostic Imaging/mt [Methods] | *Drug-Eluting Stents | Follow-Up Studies | Humans | *Percutaneous Coronary Intervention/mt [Methods] | Time Factors | *Tissue Scaffolds | Tomography, Optical CoherenceInstitution(s): MedStar Heart & Vascular InstituteActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access online Digital Object Identifier: (Click here) Abbreviated citation: Catheter Cardiovasc Interv. 88(S1):38-53, 2016 Nov.Local Holdings: Available online from MWHC library: 1996 - present, Available in print through MWHC library: 1996 - 2006.Abstract: Fully bioresorbable scaffolds (BRS) represent a novel approach for the percutaneous treatment of coronary artery stenosis, providing temporary vessel scaffolding with drug-eluting capability during the restenosis-prone phase of the vascular healing. Beyond this initial critical period, when mechanical scaffolding support is no longer necessary, the device is bioresorbed, restoring the normal vascular physiology with the aim to eliminate the long-term safety concerns related to permanent metallic implants. Nonetheless, current BRS technology suffers from limited mechanical properties as compared to available metallic platforms, requiring careful attention to lesion preparation, accurate vessel sizing, and implantation technique. Intravascular imaging has played an important role in providing knowledge on the acute effects after BRS deployment, and it helped refine the current technique of BRS implantation. In addition, extensive work with multiple intravascular imaging modalities have also contributed to the understanding of the unique dynamic vascular changes that are experienced in the treated segment from post-implantation up to complete device bioresorption. In this manuscript, we review the role of invasive imaging modalities-from angiography to sound- and light-based techniques-to guide BRS implantation procedures, to assess its acute results postimplantation, and the changes experienced in the long-term until complete bioresorption has ensued. � 2016 Wiley Periodicals, Inc.Abstract: Copyright � 2016 Wiley Periodicals, Inc.

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