Corticosteroid or hyaluronic acid injections to the carpometacarpal joint of the thumb joint are associated with early complications after subsequent surgery.

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Citation: Journal of Hand Surgery: European Volume. 43(10):1106-1110, 2018 Dec.PMID: 30335596Institution: Curtis National Hand CenterForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Carpometacarpal Joints/su [Surgery] | *Glucocorticoids/ae [Adverse Effects] | *Hyaluronic Acid/ae [Adverse Effects] | *Osteoarthritis/su [Surgery] | *Postoperative Complications | *Thumb/su [Surgery] | Diabetes Complications | Humans | Injections, Intra-Articular/ae [Adverse Effects] | Injections, Intra-Articular/sn [Statistics & Numerical Data] | Osteoarthritis/dt [Drug Therapy] | Preoperative Care | Smoking/ae [Adverse Effects] | Viscosupplements/ae [Adverse Effects]Year: 2018ISSN:
  • 0266-7681
Name of journal: The Journal of hand surgery, European volumeAbstract: Truven MarketScan Databases were used to identify patients with thumb carpometacarpal arthritis who underwent surgical treatment. Pre-operative corticosteroid or hyaluronic acid injections were identified, as were post-operative complications. Multivariable regressions assessed the relationship between injections and complications. Of 16,268 patients, 4462 had steroid injections and 252 received hyaluronic acid injections. Twenty-one per cent (3381 patients) had post-operative complications. Diabetes and smoking increased the odds of complications in all models. Odds of any complication, most notably infectious complications, were increased 20% by corticosteroids (OR 1.2; 95% CI: 1.1 to 1.3). More than three injections increased the odds of a complication by 70% (OR 1.7; 95% CI: 1.3 to 2.1). Hyaluronic acid increased the odds of wound-healing complications by 110% (OR 2.1; 95% CI: 1.3 to 3.4). Corticosteroid and hyaluronic acid injections for thumb carpometacarpal arthritis increase the odds of post-operative complications. Level of evidence: IV.All authors: Chung KC, Giladi AM, Rahgozar P, Zhong LFiscal year: FY2019Digital Object Identifier: Date added to catalog: 2018-11-02
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Journal Article MedStar Authors Catalog Article 30335596 Available 30335596

Truven MarketScan Databases were used to identify patients with thumb carpometacarpal arthritis who underwent surgical treatment. Pre-operative corticosteroid or hyaluronic acid injections were identified, as were post-operative complications. Multivariable regressions assessed the relationship between injections and complications. Of 16,268 patients, 4462 had steroid injections and 252 received hyaluronic acid injections. Twenty-one per cent (3381 patients) had post-operative complications. Diabetes and smoking increased the odds of complications in all models. Odds of any complication, most notably infectious complications, were increased 20% by corticosteroids (OR 1.2; 95% CI: 1.1 to 1.3). More than three injections increased the odds of a complication by 70% (OR 1.7; 95% CI: 1.3 to 2.1). Hyaluronic acid increased the odds of wound-healing complications by 110% (OR 2.1; 95% CI: 1.3 to 3.4). Corticosteroid and hyaluronic acid injections for thumb carpometacarpal arthritis increase the odds of post-operative complications. Level of evidence: IV.

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