Idiopathic toxic epidermal necrolysis in an adolescent.

MedStar author(s):
Citation: Pediatric Dermatology. 36(4):550-551, 2019 Jul.PMID: 30931535Institution: MedStar Washington Hospital CenterDepartment: DermatologyForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Pharyngitis/di [Diagnosis] | *Stevens-Johnson Syndrome/et [Etiology] | *Stevens-Johnson Syndrome/pa [Pathology] | *Streptococcal Infections/pp [Physiopathology] | Adolescent | Biopsy, Needle | Female | Follow-Up Studies | Humans | Immunohistochemistry | Pharyngitis/mi [Microbiology] | Severity of Illness Index | Stevens-Johnson Syndrome/th [Therapy] | Time FactorsYear: 2019ISSN:
  • 0736-8046
Name of journal: Pediatric dermatologyAbstract: A 10-year-old girl, suspected 2 days prior to have streptococcal pharyngitis, presented with diffuse erythema, tense bullae, Nikolsky-positive desquamation, as well as ulcerations of her oral and genital mucosa. She denied recent travel, sick contacts, or preceding and concurrent use of medications, including over-the-counter and herbal supplements. A comprehensive viral polymerase chain reaction (PCR) panel, Mycoplasma pneumoniae PCR and IgM, streptococcal molecular antigen test, urine culture, blood culture, and rheumatologic serologies were negative. Based on the patient's clinical presentation and biopsy results, she was diagnosed with idiopathic toxic epidermal necrolysis.Copyright (c) 2019 Wiley Periodicals, Inc.All authors: Maiman RE, Marathe K, O'Brien KFFiscal year: FY2020Digital Object Identifier: Date added to catalog: 2019-07-24
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Journal Article MedStar Authors Catalog Article 30931535 Available 30931535

A 10-year-old girl, suspected 2 days prior to have streptococcal pharyngitis, presented with diffuse erythema, tense bullae, Nikolsky-positive desquamation, as well as ulcerations of her oral and genital mucosa. She denied recent travel, sick contacts, or preceding and concurrent use of medications, including over-the-counter and herbal supplements. A comprehensive viral polymerase chain reaction (PCR) panel, Mycoplasma pneumoniae PCR and IgM, streptococcal molecular antigen test, urine culture, blood culture, and rheumatologic serologies were negative. Based on the patient's clinical presentation and biopsy results, she was diagnosed with idiopathic toxic epidermal necrolysis.

Copyright (c) 2019 Wiley Periodicals, Inc.

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