MedStar Authors catalog › Details for: The influence of coronary plaque morphology assessed by optical coherence tomography on final microvascular function after stenting in patients with ST-elevation myocardial infarction.
The influence of coronary plaque morphology assessed by optical coherence tomography on final microvascular function after stenting in patients with ST-elevation myocardial infarction. Journal: Coronary artery disease. Published: 2017 ISSN: 0954-6928. UI/PMID: 27926579. Subject(s): Aged | Angioplasty, Balloon, Coronary/ae [Adverse Effects] | *Angioplasty, Balloon, Coronary/is [Instrumentation] | Cardiac Catheterization | Coronary Angiography | *Coronary Circulation | *Coronary Vessels/dg [Diagnostic Imaging] | Coronary Vessels/pa [Pathology] | Coronary Vessels/pp [Physiopathology] | Electrocardiography | Female | Humans | Male | *Microcirculation | Middle Aged | *Plaque, Atherosclerotic | Predictive Value of Tests | Prospective Studies | ST Elevation Myocardial Infarction/dg [Diagnostic Imaging] | ST Elevation Myocardial Infarction/pa [Pathology] | ST Elevation Myocardial Infarction/pp [Physiopathology] | *ST Elevation Myocardial Infarction/th [Therapy] | *Stents | Time Factors | *Tomography, Optical Coherence | Treatment Outcome | Vascular Resistance Institution(s): MedStar Heart & Vascular Institute Activity type: Journal Article. Medline article type(s): Journal Article Online resources: Click here to access online Digital Object Identifier: https://dx.doi.org/10.1097/MCA.0000000000000458 (Click here) Abbreviated citation: Coron Artery Dis. 28(3):198-208, 2017 May. Local Holdings: Available online from MWHC library: February 2000 - present. Abstract: OBJECTIVES: The index of microcirculatory resistance (IMR) provides a reproducible assessment of the status of coronary microvasculature in patients with ST-elevation myocardial infarction (STEMI). Frequency-domain optical coherence tomography (FD-OCT) enables detailed assessment of the morphology of coronary plaque.We sought to determine the influence of the initial culprit coronary plaque anatomy within the infarct-related artery on IMR after stenting in STEMI. Abstract: PATIENTS AND METHODS: In 25 STEMI patients IMR was measured immediately before and after stent implantation. FD-OCT imaging was performed at the same time points and atherothrombotic volume (ATV) before stenting, prolapsed+floating ATV after stenting and DELTAATV was measured using three different strategies. Abstract: RESULTS: There were no relationships between preprocedural IMR and FD-OCT parameters. Prestenting IMR was related only to pain to wire time (P: 0.02). Irrespective of the method adopted, the final IMR was related to prestenting ATV (p: 0.44, P: 0.03 for method I, p: 0.48, P: 0.02 for method II and p: 0.30, P: 0.06 for method III) and DELTAATV (p: 0.41, P: 0.04 for method II and p: 0.44, P: 0.03 for method III).
Abstract: CONCLUSION: IMR measured before stenting is independent of the appearances of the culprit coronary plaque within the infarct-related artery. IMR after stenting, and more importantly, the change in IMR after stenting, reflect the degree of distal embolization during stent implantation.