Takotsubo syndrome: The past, the present and the future.

MedStar author(s):
Citation: World Journal of Cardiology. 11(9):213-216, 2019 Sep 26.PMID: 31572564Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): EditorialSubject headings: IN PROCESS -- NOT YET INDEXEDYear: 2019Name of journal: World journal of cardiologyAbstract: Takotsubo syndrome is a wide spectrum disease with a dramatic clinical presentation mimicking acute coronary syndrome albeit without obstructive coronary disease and typically manifests in the backdrop of intense emotional or physical trigger. Pathophysiology is incompletely understood with multifactorial mechanistic pathways circling around a heart-brain-endocrine axis. Several anatomic and phenotypic variants exist with varied clinical manifestations. The aftermath of Takotsubo syndrome is not always benign and both short- and long-term complications can occur which may impact its prognosis. Several gaps in knowledge exist providing an impetus for tremendous future research opportunities. Copyright (c)The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.All authors: Ahmad SA, Chhabra L, Khalid N, Sareen PFiscal year: FY2020Digital Object Identifier: Date added to catalog: 2019-10-14
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Journal Article MedStar Authors Catalog Article 31572564 Available 31572564

Takotsubo syndrome is a wide spectrum disease with a dramatic clinical presentation mimicking acute coronary syndrome albeit without obstructive coronary disease and typically manifests in the backdrop of intense emotional or physical trigger. Pathophysiology is incompletely understood with multifactorial mechanistic pathways circling around a heart-brain-endocrine axis. Several anatomic and phenotypic variants exist with varied clinical manifestations. The aftermath of Takotsubo syndrome is not always benign and both short- and long-term complications can occur which may impact its prognosis. Several gaps in knowledge exist providing an impetus for tremendous future research opportunities. Copyright (c)The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

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