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Neurogenic Stunned Myocardium in Severe Neurological Injury. [Review]

MedStar author(s):

Citation: Current Neurology & Neuroscience Reports. 19(11):90, 2019 11 13.PMID: 31720870Institution: MedStar Heart & Vascular Institute | MedStar Washington Hospital CenterDepartment: Neurosurgery | Surgery/Surgical Critical CareForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Donor Selection/mt [Methods] | *Myocardial Stunning | Acute Coronary Syndrome/di [Diagnosis] | Diagnosis, Differential | Humans | Myocardial Stunning/di [Diagnosis] | Myocardial Stunning/ep [Epidemiology] | Myocardial Stunning/pp [Physiopathology] | Myocardial Stunning/th [Therapy]Year: 2019 ISSN:

1528-4042

Name of journal: Current neurology and neuroscience reportsAbstract: PURPOSE OF REVIEW: Neurogenic stunned myocardium (NSM) is a poorly recognized cardiac manifestation of neurological illness. This review addresses the contemporary understanding of NSM pathophysiology, epidemiology, diagnosis, and clinical management.RECENT FINDINGS: While the precise pathophysiology and diagnosis remain unclear, NSM is phenotypically atypical stress cardiomyopathy that can be partially attributed to excess catecholaminergic toxicity. NSM is a diagnosis of exclusion where electrocardiography, echocardiography, and cardiac biomarkers are frequently abnormal. Clinical expertise is crucial to evaluate and differentiate NSM from acute coronary syndrome and in the evaluation of potential cardiac transplantation donors after unsalvageable severe neurological injury. Neurogenic stunned myocardium is a relatively common and clinically impactful condition. More research is needed, particularly to refine clinical prognostication of NSM and rule out intrinsic cardiac injury in order to optimize donor candidacy in the event of brain death.All authors: Barnett CF, Chang JJ, Kenigsberg BB, Mai JCOriginally published: Current Neurology & Neuroscience Reports. 19(11):90, 2019 Nov 13.Fiscal year: FY2020Digital Object Identifier:

https://dx.doi.org/10.1007/s11910-019-0999-7

Date added to catalog: 2019-12-04

Holdings ( 1 )
Title notes ( 3 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	31720870	Available		31720870

PURPOSE OF REVIEW: Neurogenic stunned myocardium (NSM) is a poorly recognized cardiac manifestation of neurological illness. This review addresses the contemporary understanding of NSM pathophysiology, epidemiology, diagnosis, and clinical management.

RECENT FINDINGS: While the precise pathophysiology and diagnosis remain unclear, NSM is phenotypically atypical stress cardiomyopathy that can be partially attributed to excess catecholaminergic toxicity. NSM is a diagnosis of exclusion where electrocardiography, echocardiography, and cardiac biomarkers are frequently abnormal. Clinical expertise is crucial to evaluate and differentiate NSM from acute coronary syndrome and in the evaluation of potential cardiac transplantation donors after unsalvageable severe neurological injury. Neurogenic stunned myocardium is a relatively common and clinically impactful condition. More research is needed, particularly to refine clinical prognostication of NSM and rule out intrinsic cardiac injury in order to optimize donor candidacy in the event of brain death.

English