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Recognizing Drug Hypersensitivity in Pigmented Skin. [Review]

MedStar author(s):

Citation: Immunology & Allergy Clinics of North America. 42(2):219-238, 2022 May.PMID: 35469616Institution: MedStar Washington Hospital CenterDepartment: DermatologyForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Drug Hypersensitivity | Drug Hypersensitivity/di [Diagnosis] | Drug Hypersensitivity/th [Therapy] | Humans | SkinYear: 2022 ISSN:

0889-8561

Name of journal: Immunology and allergy clinics of North AmericaAbstract: The imagery of pigmented skin is underrepresented in teaching materials such as textbooks, journals, and online references, and this has resulted in poorer diagnostic and management outcomes of skin pathology, including delayed cutaneous drug hypersensitivity reactions. In this review, we use clinical images to highlight factors that impact clinical presentations and sequelae of drug hypersensitivity reactions in pigmented skin compared with nonpigmented skin. We describe clinical features in some anatomic sites that aid diagnosis or are associated with more severe sequelae. Finally, we discuss strategies that may aid the diagnosis and management of these reactions in pigmented skin. Copyright ♭ 2022 Elsevier Inc. All rights reserved.All authors: Lehloenya RJ, Pasieka HB, Peter J, Phillips EJOriginally published: Immunology & Allergy Clinics of North America. 42(2):219-238, 2022 May.Fiscal year: FY2022 Digital Object Identifier:

https://dx.doi.org/10.1016/j.iac.2022.01.005

Date added to catalog: 2022-05-11

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Title notes ( 2 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	35469616	Available		35469616

The imagery of pigmented skin is underrepresented in teaching materials such as textbooks, journals, and online references, and this has resulted in poorer diagnostic and management outcomes of skin pathology, including delayed cutaneous drug hypersensitivity reactions. In this review, we use clinical images to highlight factors that impact clinical presentations and sequelae of drug hypersensitivity reactions in pigmented skin compared with nonpigmented skin. We describe clinical features in some anatomic sites that aid diagnosis or are associated with more severe sequelae. Finally, we discuss strategies that may aid the diagnosis and management of these reactions in pigmented skin. Copyright ♭ 2022 Elsevier Inc. All rights reserved.

English