Current and novel multi-imaging modalities to assess retinal oxygenation and blood flow. [Review]

MedStar author(s):
Citation: Eye. 35(11):2962-2972, 2021 11.PMID: 34117399Institution: MedStar Union Memorial HospitalDepartment: Internal Medicine ResidencyForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Oxygen | *Retinal Diseases | Diagnostic Imaging | Humans | Regional Blood Flow | Retina/dg [Diagnostic Imaging] | Retinal Diseases/dg [Diagnostic Imaging]Year: 2021ISSN:
  • 0950-222X
Name of journal: Eye (London, England)Abstract: Retinal ischemia characterizes the underlying pathology in a multitude of retinal diseases that can ultimately lead to vision loss. A variety of novel imaging modalities have been developed to characterize retinal ischemia by measuring retinal oxygenation and blood flow in-vivo. These technologies offer valuable insight into the earliest pathophysiologic changes within the retina and provide physicians and researchers with new diagnostic and monitoring capabilities. Future retinal imaging technologies with the capability to provide affordable, noninvasive, and comprehensive data on oxygen saturation, vasculature, and blood flow mechanics are needed. This review will highlight current and future trends in multimodal imaging to assess retinal blood flow and oxygenation.All authors: Gehlbach PL, Jiramongkolchai K, Marino MJ, Rege AOriginally published: Eye. 2021 Jun 11Fiscal year: FY2022Fiscal year of original publication: FY2021Digital Object Identifier: Date added to catalog: 2021-07-19
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Journal Article MedStar Authors Catalog Article 34117399 Available 34117399

Retinal ischemia characterizes the underlying pathology in a multitude of retinal diseases that can ultimately lead to vision loss. A variety of novel imaging modalities have been developed to characterize retinal ischemia by measuring retinal oxygenation and blood flow in-vivo. These technologies offer valuable insight into the earliest pathophysiologic changes within the retina and provide physicians and researchers with new diagnostic and monitoring capabilities. Future retinal imaging technologies with the capability to provide affordable, noninvasive, and comprehensive data on oxygen saturation, vasculature, and blood flow mechanics are needed. This review will highlight current and future trends in multimodal imaging to assess retinal blood flow and oxygenation.

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