Citation: Cureus. 12(5):e7998, 2020 May 06..Journal: Cureus.Published: ; 2020ISSN: 2168-8184.Full author list: Ali L; Ghazzal A; Sallam T; Zaghlol R; Cuneo B.UI/PMID: 32523852.Subject(s): IN PROCESS -- NOT YET INDEXEDInstitution(s): MedStar Washington Hospital CenterDepartment(s): Medicine/Internal Medicine | Medicine/Pulmonary-Critical CareActivity type: Journal Article.Medline article type(s): Case ReportsOnline resources: Click here to access onlineDigital Object Identifier: https://dx.doi.org/10.7759/cureus.7998 (Click here)Abbreviated citation: Cureus. 12(5):e7998, 2020 May 06.Abstract: Cardiac tumors are relatively rare. Secondary cardiac tumors are by far more common than primary cardiac tumors. Cardiac involvement may occur secondary to hematogenous metastases, direct invasion, or tumor growth into the venous system and extension into the right atrium. Patients can present with a spectrum of conditions, including embolization, obstruction of ventricular outflow tracts, direct invasion of myocardium causing impaired myocardial function, invasion of surrounding tissue, interference with valvular function causing valvular regurgitation, or constitutional non-specific signs and symptoms. Imaging modalities are essential for diagnosis. Management is mostly surgical, but can include other medical strategies as well. We present a case of a 65-year-old male with hepatocellular carcinoma with direct invasion to the heart through the venous system. Copyright (c) 2020, Ali et al.