Hepatopulmonary syndrome: An update. [Review]

MedStar author(s):
Citation: World Journal of Hepatology. 13(11):1699-1706, 2021 Nov 27.PMID: 34904039Institution: MedStar Washington Hospital CenterDepartment: Internal Medicine ResidencyForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: IN PROCESS -- NOT YET INDEXEDYear: 2021Name of journal: World journal of hepatologyAbstract: Hepatopulmonary syndrome (HPS) is characterized by defects in oxygenation caused by intra-pulmonary vasodilation occurring because of chronic liver disease, portal hypertension, or congenital portosystemic shunts. Clinical implications of portal hypertension are very well-known, however, awareness of its effect on multiple organs such as the lungs are less known. The presence of HPS in chronic liver disease is associated with increased mortality. Medical therapies available for HPS have not been proven effective and definitive treatment for HPS is mainly liver transplantation (LT). LT improves mortality for patients with HPS drastically. This article provides a review on the definition, clinical presentation, diagnosis, and management of HPS. Copyright (c)The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.All authors: Gandhi KD, Sharma M, Surani S, Taweesedt PTFiscal year: FY2022Digital Object Identifier: Date added to catalog: 2022-01-25
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Journal Article MedStar Authors Catalog Article 34904039 Available 34904039

Hepatopulmonary syndrome (HPS) is characterized by defects in oxygenation caused by intra-pulmonary vasodilation occurring because of chronic liver disease, portal hypertension, or congenital portosystemic shunts. Clinical implications of portal hypertension are very well-known, however, awareness of its effect on multiple organs such as the lungs are less known. The presence of HPS in chronic liver disease is associated with increased mortality. Medical therapies available for HPS have not been proven effective and definitive treatment for HPS is mainly liver transplantation (LT). LT improves mortality for patients with HPS drastically. This article provides a review on the definition, clinical presentation, diagnosis, and management of HPS. Copyright (c)The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

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