Durable Polymer Drug Eluting Stent-Induced Kounis Syndrome and Eosinophilia Requiring Long-term Immunosuppression.

MedStar author(s):
Citation: Canadian Journal of Cardiology. 38(3):398-400, 2022 03.PMID: 34902455Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Case ReportsSubject headings: *Drug-Eluting Stents/ae [Adverse Effects] | *Eosinophilia | *Kounis Syndrome | *Nickel | *Percutaneous Coronary Intervention | *Prednisone/ad [Administration & Dosage] | Aged, 80 and over | Diagnosis, Differential | Eosinophilia/di [Diagnosis] | Eosinophilia/et [Etiology] | Humans | Immunosuppressive Agents/ad [Administration & Dosage] | Kounis Syndrome/di [Diagnosis] | Kounis Syndrome/dt [Drug Therapy] | Kounis Syndrome/et [Etiology] | Kounis Syndrome/pp [Physiopathology] | Male | Metals, Heavy/ae [Adverse Effects] | Metals, Heavy/an [Analysis] | Nickel/ae [Adverse Effects] | Nickel/an [Analysis] | Non-ST Elevated Myocardial Infarction/su [Surgery] | Percutaneous Coronary Intervention/ae [Adverse Effects] | Percutaneous Coronary Intervention/is [Instrumentation] | Percutaneous Coronary Intervention/mt [Methods] | Skin Tests/mt [Methods]Year: 2022ISSN:
  • 0828-282X
Name of journal: The Canadian journal of cardiologyAbstract: There are no reports of systemic eosinophilic reactions to durable polymer coated drug eluting stents (DP-DES) and a consensus statement indicates that these devices should be considered in nickel allergy. We present a case of in-stent thrombosis, eosinophilia, and rash consistent with allergic myocardial infarction, a presentation of Kounis syndrome, in the context of metal allergy to DP-DES requiring long-term immunosuppression. Copyright (c) 2021. Published by Elsevier Inc.All authors: Bortnick AE, Boucher T, Hashim H, Jerschow E, Shah AMOriginally published: Canadian Journal of Cardiology. 2021 Dec 10Fiscal year: FY2022Digital Object Identifier: Date added to catalog: 2022-01-25
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Journal Article MedStar Authors Catalog Article 34902455 Available 34902455

There are no reports of systemic eosinophilic reactions to durable polymer coated drug eluting stents (DP-DES) and a consensus statement indicates that these devices should be considered in nickel allergy. We present a case of in-stent thrombosis, eosinophilia, and rash consistent with allergic myocardial infarction, a presentation of Kounis syndrome, in the context of metal allergy to DP-DES requiring long-term immunosuppression. Copyright (c) 2021. Published by Elsevier Inc.

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