Use of whole-genome sequencing to guide a Clostridioides difficile diagnostic stewardship program. 

 -  2019 
<br/><br/> Whole-genome sequencing (WGS) has yielded new insights into the transmission patterns of healthcare facility-onset Clostridioides difficile infection (HO-CDI). WGS results prompted a focused diagnostic stewardship program, which was associated with a significant and sustained decrease in HO-CDI at large, urban hospital. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>0899-823X 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*Clostridium difficile/ge [Genetics]<br/>*Clostridium difficile/ip [Isolation & Purification]<br/>*Clostridium Infections/di [Diagnosis]<br/>*Clostridium Infections/tm [Transmission]<br/>*Cross Infection/di [Diagnosis]<br/>Cross Infection/mi [Microbiology]<br/>Cross Infection/tm [Transmission]<br/>Genome, Bacterial<br/>Health Facilities<br/>Humans<br/>Ribotyping<br/>Whole Genome Sequencing
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar Health<br/>MedStar Institute for Quality and Safety<br/>MedStar Washington Hospital Center
<br/><br/><label>Index Terms--Occupation: </label><br/>Information Services<br/>Medicine/Infectious Diseases<br/>Medicine/Internal Medicine<br/>Pathology and Laboratory Medicine
<br/><br/><label>Index Terms--Function: </label><br/>Journal Article