TY - BOOK AU - Miodovnik, Menachem TI - Association of cord blood magnesium concentration and neonatal resuscitation SN - 0022-3476 KW - *Fetal Blood/ch [Chemistry] KW - *Magnesium Sulfate/bl [Blood] KW - *Resuscitation/sn [Statistics & Numerical Data] KW - Female KW - Humans KW - Infant, Newborn KW - Male KW - Prospective Studies KW - MedStar Health Research Institute KW - Journal Article KW - Multicenter Study KW - Randomized Controlled Trial KW - Research Support, N.I.H., Extramural N1 - Available online from MWHC library: 1995 - present N2 - CONCLUSION: Cord blood Mg concentration does not correlate with the level of delivery room resuscitation of infants exposed to magnesium sulfate for fetal neuroprotection. Copyright A 2012 Mosby, Inc. All rights reserved; OBJECTIVE: To assess the relationship between umbilical cord blood magnesium concentration and level of delivery room resuscitation received by neonates; RESULTS: There was no relationship between cord blood Mg and delivery room resuscitation (OR, 0.92 for each 1.0-mEq/L increase in Mg; 95% CI, 0.83-1.03). Maternal general anesthesia was associated with increased neonatal resuscitation (OR, 2.51; 95% CI, 1.72-3.68). Each 1-week increase in gestational age at birth was associated with decreased neonatal resuscitation (OR, 0.63; 95% CI, 0.60-0.66); STUDY DESIGN: This was a secondary analysis of a controlled fetal neuroprotection trial that enrolled women at imminent risk for delivery between 24 and 31 weeks' gestation and randomly allocated them to receive either intravenous magnesium sulfate or placebo. The cohort included 1507 infants with data available on total cord blood Mg concentration and delivery room resuscitation. Multivariate logistic regression was used to estimate the association between cord blood Mg concentration and highest level of delivery room resuscitation, using the following hierarchy: none, oxygen only, bag-mask ventilation with oxygen, intubation, and chest compressions UR - http://dx.doi.org/10.1016/j.jpeds.2011.09.016 ER -