TY  - BOOK
AU  - Lipinski, Michael J
TI  - Molecule 16673-34-0: a new tool in our arsenal against inflammation
SN  - 0160-2446
KW  - *Anti-Inflammatory Agents, Non-Steroidal/tu [Therapeutic Use]
KW  - *Benzamides/tu [Therapeutic Use]
KW  - *Carrier Proteins/ai [Antagonists & Inhibitors]
KW  - *Inflammasomes/ai [Antagonists & Inhibitors]
KW  - *Myocardial Reperfusion Injury/dt [Drug Therapy]
KW  - *Sulfonamides/tu [Therapeutic Use]
KW  - Animals
KW  - Benzamides/cs [Chemical Synthesis]
KW  - Blood Glucose/me [Metabolism]
KW  - Cell Line
KW  - Macrophages/de [Drug Effects]
KW  - Male
KW  - Mice
KW  - Peritonitis/ci [Chemically Induced]
KW  - Peritonitis/pc [Prevention & Control]
KW  - Sulfonamides/cs [Chemical Synthesis]
KW  - MedStar Heart & Vascular Institute
KW  - Journal Article
N1  - Available online from MWHC library: 1996 - present
N2  - The NLRP3 inflammasome has been shown to modulate IL-1B and IL-18 production, both key molecular regulators of inflammation. This editorial discusses a new molecule 16673-34-0 that inhibits the NLRP3 inflammasome and decreases caspase 1 production following ischemia reperfusion or acute peritonitis in mice
UR  - http://dx.doi.org/10.1097/FJC.0000000000000070
ER  -