TY - BOOK AU - Balsara, Keki AU - Ben-Dor, Itsik AU - Rogers, Toby AU - Satler, Lowell F AU - Sheikh, Farooq H AU - Waksman, Ron AU - Wallace, Ryan AU - Weissman, Gaby TI - Percutaneous endovascular intervention for left ventricular assist device outflow graft obstruction: A single-center experience SN - 1878-0938 PY - 2024/// KW - IN PROCESS -- NOT YET INDEXED KW - Automated KW - MedStar Heart & Vascular Institute KW - MedStar Washington Hospital Center KW - Cardiovascular Disease Fellowship KW - Journal Article N1 - Available in print through MWHC library: 2002 - present N2 - BACKGROUND: Outflow graft obstruction (OGO) is an uncommon yet life-threatening complication in patients with left ventricular assist devices (LVADs). In this retrospective, single-center case series, we identify the baseline demographics and presenting features of patients who develop LVAD OGO and the procedural details and outcomes surrounding percutaneous endovascular intervention (PEI); CONCLUSION: In our single-center experience, PEI can be a safe and effective treatment for LVAD OGO. Copyright © 2024. Published by Elsevier Inc; METHODS: We conducted a retrospective review of patients with LVADs at our institution between January 2010 and February 2023 who developed OGO and were treated with PEI. Details of the PEI including procedure time, fluoroscopy time, contrast use, stent size, number of stents, change in gradient, and change in flow after intervention were collected; RESULTS: A total of 12 patients who had 14 cases of OGO were identified from January 2010 to February 2023. The average age at presentation was 64.78 years. Nine of the 14 cases occurred in male patients. Eleven of the 14 cases occurred with Heartware devices (2 recurrences), 2 in Heartmate 2 and 1 in Heartmate 3. Notable procedural details include a mean procedure time of 90.86 min and mean contrast use of 162.5 mL. The initial gradient across the OGO was reduced by an average of 72 %, to a mean post-PEI of 11.57 mmHg. The average number of stents to achieve this gradient was around 2.08, with the most common stent diameter being 10 mm. Thirty-day mortality after PEI was 7 % (1/14) in this high-risk patient population UR - https://dx.doi.org/10.1016/j.carrev.2024.05.017 ER -