TY  - BOOK
AU  - Doshi, Saumil
AU  - Kerai, Ajay
AU  - Laleker, Ashley
TI  - Fungal Foe and Mechanical Hearts: A Retrospective Case Series on Candida auris Bloodstream Infection With Left Ventricular Assist Devices
SN  - 2328-8957
PY  - 2024///
KW  - Automated
KW  - MedStar Washington Hospital Center
KW  - Department of Internal Medicine/Infectious Disease
KW  - Internal Medicine Residency
KW  - Physical Medicine and Rehabilitation
KW  - Case Reports
KW  - Journal Article
N2  - No guidelines currently exist for the management of Candida auris bloodstream infection in patients with left ventricular assist devices (LVADs). We aim to share our management experience through this retrospective case series outlining 15 episodes of C auris candidemia identified in 7 patients over 18 months. The initial source of candidemia was central venous catheter in 5 patients, driveline exit site infection in 1 patient, and possible pump infection in 1 patient. All patients were initially treated with micafungin. Despite susceptibility to micafungin, 4 patients experienced recurrent C auris candidemia. All patients died within 1 year of their first episode of C auris candidemia. Source control is challenging in patients with LVADs, and strict infection prevention measures should be practiced. More studies are needed to evaluate the role of newer antifungal agents, use of combination antifungal regimens, and impact on morbidity in patients with LVADs. Copyright © The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America
UR  - https://dx.doi.org/10.1093/ofid/ofae286
ER  -