TY - BOOK AU - Abusnina, Waiel TI - Impact of anemia on outcomes and resource utilization in patients with myocardial infarction: A national database analysis SN - 0167-5273 PY - 2024/// KW - *Anemia KW - *Databases, Factual KW - *Myocardial Infarction KW - Aged KW - Aged, 80 and over KW - Anemia/ec [Economics] KW - Anemia/ep [Epidemiology] KW - Anemia/th [Therapy] KW - Female KW - Health Resources/ec [Economics] KW - Health Resources/sn [Statistics & Numerical Data] KW - Hospital Mortality/td [Trends] KW - Hospitalization/ec [Economics] KW - Hospitalization/sn [Statistics & Numerical Data] KW - Humans KW - Length of Stay/sn [Statistics & Numerical Data] KW - Male KW - Middle Aged KW - Myocardial Infarction/co [Complications] KW - Myocardial Infarction/ec [Economics] KW - Myocardial Infarction/ep [Epidemiology] KW - Myocardial Infarction/th [Therapy] KW - Retrospective Studies KW - United States/ep [Epidemiology] KW - Automated KW - MedStar Washington Hospital Center KW - Advanced Cardiac Catheterization Research Fellowship KW - Journal Article N2 - BACKGROUND: Although anemia is common in patients with myocardial infarction (MI), management remains controversial. We quantified the association of anemia with in-hospital outcomes and resource utilization in patients admitted with MI using a large national database; CONCLUSION: In MI patients, anemia was associated with higher in-hospital mortality, adverse events, total cost, and length of stay. Transfusion was associated with increased mortality, and its role in MI requires further research. Copyright © 2023. Published by Elsevier B.V; METHODS: All hospitalizations with a primary diagnosis code for acute MI in the National Inpatient Sample (NIS) between 2014 and 2018 were identified. Among these hospitalizations, patients with anemia were identified using a secondary diagnosis code. Data on demographic and clinical variables were collected. Outcomes of interest included in-hospital adverse events, length of stay (LOS), and total cost. Multivariable logistic regression and generalized linear models were used to evaluate the relationship between anemia and outcomes; RESULTS: Among 1,113,181 MI hospitalizations, 254,816 (22.8%) included concomitant anemia. Anemic patients were older and more likely to be women. After adjustment for demographics and comorbidities, anemia was associated with higher mortality (7.1 vs. 4.3%; odds ratio 1.09; 95% confidence interval [CI] 1.07-1.12, p < 0.001). Anemia was also associated with a mean of 2.71 days longer LOS (average marginal effects [AME] 2.71; 95% CI 2.68-2.73, p < 0.05), and UR - https://dx.doi.org/10.1016/j.ijcard.2024.132111 ER -