TY  - BOOK
AU  - Basyal, Binaya
AU  - Bigham, Grace
AU  - Hadadi, Cyrus A
AU  - Lam, Phillip H
AU  - Lawrence, Luke
AU  - Meda, Namratha S
AU  - Najjar, Samer S
AU  - Oates, Connor
AU  - Rao, Sriram
AU  - Shah, Manish H
AU  - Sheikh, Farooq H
TI  - Impact of Cardiac Resynchronization Therapy on Ventricular Arrhythmias and Survival After Durable Left Ventricular Assist Device Implantation
SN  - 1058-2916
PY  - 2024///
KW  - Automated
KW  - IN PROCESS -- NOT YET INDEXED
KW  - MedStar Heart & Vascular Institute
KW  - MedStar Washington Hospital Center
KW  - Cardiovascular Disease Fellowship
KW  - Clinical Cardiac Electrophysiology Fellowship
KW  - Internal Medicine Residency
KW  - MedStar Georgetown University Hospital/MedStar Washington Hospital Center
KW  - Journal Article
N1  - Available online from MWHC library: 2000 - present, Available in print through MWHC library: 1999 - 2003
N2  - The impact of cardiac resynchronization therapy (CRT) in patients receiving durable left ventricular assist device (LVAD) implantation remains unclear and there is no consensus regarding postoperative management. We sought to determine the impact of postoperative management of CRT on clinical outcomes following LVAD implantation. A total of 789 patients underwent LVAD implantation at our institution from 2007 to 2022 including 195 patients (24.7%) with preoperative CRT. Patients with preoperative CRT were significantly older and more frequently received an LVAD as destination therapy compared to patients without preoperative CRT. After LVAD implantation, 85 patients had CRT programmed "off" and 74 patients had CRT programmed "on." The risk of mortality was significantly increased amongst patients with preoperative CRT that was turned "on" following LVAD implantation compared to patients with preoperative CRT turned "off" following implant (subdistribution hazard ratio [sdHR] = 1.54; 1.06-2.37 95% confidence interval [CI]; p = 0.036). There was no significant difference between incidence of ventricular arrhythmias in patients with and without postoperative CRT "on" (35.1% vs. 48.2%; p = 0.095). Additional clinical trials are warranted to determine the best CRT programming strategy following LVAD implantation. Copyright © ASAIO 2024
UR  - https://dx.doi.org/10.1097/MAT.0000000000002279
ER  -