Two cases of metallosis from metal-on-polyethylene total hips: an emerging problem. 

 -  2015 
<br/><br/> This report describes 2 cases of metallosis from metal-on-polyethylene total hip replacements. Case 1 involved a Stryker rejuvenate implant, which has since been recalled. This patient had minimal symptoms, an elevated cobalt level, and loosening. The patient in case 2 had a Dupuys Pinnacle system, with symptoms of weakness, rash, and hip pain. Abnormal laboratory values include elevated sedimentation rate, C-reactive protein, creatinine, cobalt, and decreased hematocrit. Magnetic resonance imaging revealed synovial thickening and extracapsular edema. Although metallosis is a well-established complication of metal-on-metal implants, emerging data reveal that it also may be a problem in non-metal-on-metal implants such as either metal-on-polyethylene or ceramic-on-polyethylene implants, perhaps related to modular corrosion. Copyright © 2015 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>1934-1482 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*Cobalt/bl [Blood]<br/>*Cobalt/to [Toxicity]<br/>*Prosthesis Design<br/>Aged, 80 and over<br/>Arthroplasty, Replacement, Hip<br/>Female<br/>Hip Prosthesis/ae [Adverse Effects]<br/>Humans<br/>Male<br/>Middle Aged<br/>Polyethylene
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar National Rehabilitation Network
<br/><br/><label>Index Terms--Function: </label><br/>Case Reports<br/>Journal Article