TY - BOOK AU - Lhermusier, Thibault AU - Magalhaes, Marco A AU - Ota, Hideaki AU - Pichard, Augusto D AU - Satler, Lowell F AU - Suddath, William O AU - Torguson, Rebecca AU - Waksman, Ron TI - Comparison of clinical outcomes in patients presenting with an acute coronary syndrome due to stent thrombosis or saphenous vein graft occlusion and undergoing percutaneous coronary intervention SN - 1878-0938 KW - *Acute Coronary Syndrome/th [Therapy] KW - *Coronary Artery Bypass/ae [Adverse Effects] KW - *Coronary Restenosis/co [Complications] KW - *Drug-Eluting Stents/ae [Adverse Effects] KW - *Graft Occlusion, Vascular/co [Complications] KW - *Percutaneous Coronary Intervention/mt [Methods] KW - Academic Medical Centers KW - Acute Coronary Syndrome/di [Diagnosis] KW - Acute Coronary Syndrome/et [Etiology] KW - Acute Coronary Syndrome/mo [Mortality] KW - Aged KW - Aged, 80 and over KW - Analysis of Variance KW - Cause of Death KW - Chi-Square Distribution KW - Cohort Studies KW - Coronary Artery Bypass/mt [Methods] KW - Coronary Restenosis/ra [Radiography] KW - Coronary Restenosis/th [Therapy] KW - District of Columbia KW - Female KW - Graft Occlusion, Vascular/ra [Radiography] KW - Graft Occlusion, Vascular/th [Therapy] KW - Hospital Mortality/td [Trends] KW - Humans KW - Kaplan-Meier Estimate KW - Male KW - Middle Aged KW - Percutaneous Coronary Intervention/mo [Mortality] KW - Prognosis KW - Retrospective Studies KW - Risk Assessment KW - Saphenous Vein/tr [Transplantation] KW - Survival Analysis KW - Treatment Outcome KW - MedStar Washington Hospital Center KW - MedStar Heart Institute KW - Comparative Study KW - Journal Article N1 - Available in print through MWHC library: 2002 - present N2 - BACKGROUND: Patients presenting with ST or SVG occlusion are at increased risk of adverse outcomes. There is limited literature comparing the outcome of such patients; CONCLUSIONS: As compared to patients undergoing NC-PCI, patients with ST have greater rates of in-hospital mortality and major bleeding as well as 30-day MACE rate. The 1-year MACE rate is similar in patients with ST and SVG occlusion who undergo PCI.Copyright (c) 2015. Published by Elsevier Inc; METHODS: A cohort of 415 consecutive patients presenting to the MedStar Washington Hospital Center undergoing percutaneous coronary intervention (PCI) for an acute coronary syndrome secondary to ST (n=136) or SVG occlusion (n=279) was studied. The SVG group was subdivided into patients who underwent PCI in the occluded SVG (SVG-PCI: n=75) or in the subtended native coronary artery (NC-PCI: n=204). The analyzed clinical parameters were in-hospital complications as well as 30-day and 1-year major adverse cardiac events (MACE). MACE was defined as all-cause mortality, Q-wave myocardial infarction, or target vessel revascularization; OBJECTIVE: To compare the clinical outcomes of patients undergoing percutaneous intervention for stent thrombosis (ST) or saphenous vein graft (SVG) occlusion; RESULTS: The rates of death, major bleeding, and length of hospital stay were significantly different between the ST and NC-PCI groups. The SVG-PCI group had a shorter hospital stay. The 30-day MACE rate was significantly different in the ST and NC-PCI groups (18.9% vs. 7.5%; risk ratio=0.40, 95% CI=0.20-0.81, p=0.03) but not in the ST and SVG-PCI groups (18.9% vs. 15.1%; p=0.55, risk ratio=0.80, 95% CI=0.38-1.68). There were no differences in the 1-year MACE rate UR - http://dx.doi.org/10.1016/j.carrev.2015.10.002 ER -