TY  - BOOK
AU  - Iqbal, Sara N
TI  - In vivo assessment of placental and brain volumes in growth-restricted fetuses with and without fetal Doppler changes using quantitative 3D MRI
SN  - 0743-8346
PY  - 2017///
KW  - *Brain/dg [Diagnostic Imaging]
KW  - *Fetal Development
KW  - *Fetal Growth Retardation/dg [Diagnostic Imaging]
KW  - *Imaging, Three-Dimensional
KW  - *Magnetic Resonance Imaging/mt [Methods]
KW  - *Placenta/dg [Diagnostic Imaging]
KW  - Adolescent
KW  - Adult
KW  - Brain/pa [Pathology]
KW  - Case-Control Studies
KW  - Female
KW  - Gestational Age
KW  - Humans
KW  - Longitudinal Studies
KW  - Male
KW  - Organ Size
KW  - Placenta/pa [Pathology]
KW  - Predictive Value of Tests
KW  - Pregnancy
KW  - Prospective Studies
KW  - Ultrasonography, Prenatal
KW  - Young Adult
KW  - MedStar Washington Hospital Center
KW  - Obstetrics and Gynecology/Maternal-Fetal Medicine
KW  - Journal Article
N2  - CONCLUSION: Quantitative fetal MRI can accurately detect decreased placental and brain volumes in pregnancies with FGR and may provide insight into the timing and mechanisms of brain injury in FGR.Journal of Perinatology advance online publication, 24 August 2017; doi:10.1038/jp.2017.129; OBJECTIVE: The relationship between placental and fetal brain growth is poorly understood and difficult to assess. The objective of this study was to interrogate placental and fetal brain growth in healthy pregnancies and those complicated by fetal growth restriction (FGR); RESULTS: A total of 114 women (79 controls and 35 FGR) underwent MRI (median gestational age (GA) 30 weeks, range 18 to 39). All measured volumes increased exponentially with advancing GA. Placental, total brain, cerebral and cerebellar volumes were smaller in FGR compared with controls (P<0.05). Increasing placental volume was associated with increasing cerebral and cerebellar volumes (P<0.05); STUDY DESIGN: In a prospective, observational study, pregnant women with normal pregnancies or pregnancies complicated by FGR underwent fetal magnetic resonance imaging (MRI). Placental, global and regional brain volumes were calculated
UR  - https://dx.doi.org/10.1038/jp.2017.129
ER  -