TY  - BOOK
AU  - Ben-Dor, Itsik
AU  - Buchanan, Kyle
AU  - Craig, Paige
AU  - Gai, Jiaxiang
AU  - Okubagzi, Petros
AU  - Pichard, Augusto D
AU  - Pokharel, Shreejana
AU  - Rogers, Toby
AU  - Satler, Lowell F
AU  - Torguson, Rebecca
AU  - Waksman, Ron
TI  - MynxGrip vascular closure device versus manual compression for hemostasis of percutaneous transfemoral venous access closure: Results from a prospective multicenter randomized study
SN  - 1878-0938
PY  - 2018///
KW  - *Catheterization, Peripheral
KW  - *Femoral Vein
KW  - *Hemorrhage/pc [Prevention & Control]
KW  - *Hemostatic Techniques/is [Instrumentation]
KW  - *Vascular Closure Devices
KW  - Aged
KW  - Aged, 80 and over
KW  - Catheterization, Peripheral/ae [Adverse Effects]
KW  - Equipment Design
KW  - Female
KW  - Femoral Vein/dg [Diagnostic Imaging]
KW  - Hemorrhage/di [Diagnosis]
KW  - Hemorrhage/et [Etiology]
KW  - Hemostasis
KW  - Hemostatic Techniques/ae [Adverse Effects]
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Pressure
KW  - Prospective Studies
KW  - Punctures
KW  - Time Factors
KW  - Treatment Outcome
KW  - MedStar Heart & Vascular Instituteon
KW  - Journal Article
N1  - Available in print through MWHC library: 2002 - present
N2  - CONCLUSIONS: The MynxGrip extravascular sealant is safe and effective for femoral venous access site closure; Copyright (c) 2018 Elsevier Inc. All rights reserved; METHODS AND MATERIALS: This is a multicenter, randomized, prospective study of 208 patients who were slated to undergo diagnostic/interventional procedures via femoral venous access. Patients were randomized 1:1 to receive venous hemostasis via MynxGrip (n=104) or manual compression (n=104) utilizing 5, 6, and 7 Fr sheaths. Bilateral calf and thigh circumferences were measured serially. Patients were followed up through hospital discharge. There were no differences in the baseline characteristics between the two groups; PURPOSE: Evaluate the safety of MynxGrip for common femoral vein closure; RESULTS: There was no difference between the groups for venous thrombosis, (0%, p=1). Overall, there was no significant change in access site calf (-0.18+/-1.38cm, p=0.18) or thigh diameter (0.33+/-2.86, p=0.81). In both groups, none of the patients had major or minor vascular complications, access site infection, nerve injury, or access site bleeding requiring transfusion. The pre- to post-procedure hemoglobin drop was -0.51+/-1.1 vs. -0.64+/-1.3g/dL, p=0.59 in the manual compression group and MynxGrip group, respectively. Time to hemostasis, was significantly lower in the MynxGrip group compared to the manual compression group with 0.12+/-0.89 vs. 7.6+/-5.7min, respectively (p<0.001)
UR  - https://dx.doi.org/10.1016/j.carrev.2018.03.007
ER  -