TY  - BOOK
AU  - Armonda, Rocco A
TI  - Blast-related traumatic brain injury. [Review]
SN  - 1474-4422
PY  - 2013///
KW  - *Blast Injuries
KW  - *Brain Injuries
KW  - *Post-Concussion Syndrome
KW  - *Stress Disorders, Post-Traumatic
KW  - Blast Injuries/ep [Epidemiology]
KW  - Blast Injuries/pp [Physiopathology]
KW  - Blast Injuries/th [Therapy]
KW  - Brain Injuries/ep [Epidemiology]
KW  - Brain Injuries/pp [Physiopathology]
KW  - Brain Injuries/th [Therapy]
KW  - Humans
KW  - Post-Concussion Syndrome/ep [Epidemiology]
KW  - Post-Concussion Syndrome/pp [Physiopathology]
KW  - Post-Concussion Syndrome/th [Therapy]
KW  - Stress Disorders, Post-Traumatic/ep [Epidemiology]
KW  - Stress Disorders, Post-Traumatic/pp [Physiopathology]
KW  - Stress Disorders, Post-Traumatic/th [Therapy]
KW  - MedStar Washington Hospital Center
KW  - Radiology
KW  - Journal Article
KW  - Review
N1  - Available online through MWHC library: May 2002 - present
N2  - A bomb blast may cause the full severity range of traumatic brain injury (TBI), from mild concussion to severe, penetrating injury. The pathophysiology of blast-related TBI is distinctive, with injury magnitude dependent on several factors, including blast energy and distance from the blast epicentre. The prevalence of blast-related mild TBI in modern war zones has varied widely, but detection is optimised by battlefield assessment of concussion and follow-up screening of all personnel with potential concussive events. There is substantial overlap between post-concussive syndrome and post-traumatic stress disorder, and blast-related mild TBI seems to increase the risk of post-traumatic stress disorder. Post-concussive syndrome, post-traumatic stress disorder, and chronic pain are a clinical triad in this patient group. Persistent impairment after blast-related mild TBI might be largely attributable to psychological factors, although a causative link between repeated mild TBIs caused by blasts and chronic traumatic encephalopathy has not been established. The application of advanced neuroimaging and the identification of specific molecular biomarkers in serum for diagnosis and prognosis are rapidly advancing, and might help to further categorise these injuries. Copyright  2013 Elsevier Ltd. All rights reserved
UR  - http://dx.doi.org/10.1016/S1474-4422(13)70161-3
ER  -