04378nam a22007457a 4500
190621s20192019 xxu||||| |||| 00| 0 eng d
1526-6028
Ovid MEDLINE(R)
30931727
Association Between Underweight Body Mass Index and In-Hospital Outcome in Patients Undergoing Endovascular Interventions for Peripheral Artery Disease: A Propensity Score Matching Analysis.
Journal of Endovascular Therapy. 26(3):411-417, 2019 06.
J Endovasc Ther. 26(3):411-417, 2019 06.
J Endovasc Ther. 26(3):411-417, 2019 Jun.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
2019
FY2019
ppublish
2019-06-21
Journal of Endovascular Therapy. 26(3):411-417, 2019 Jun.
CONCLUSION: Low-BMI patients with PAD have worse in-hospital survival and more adverse outcomes after EVT.
MATERIALS AND METHODS: Using weighted data from the National Inpatient Sample (NIS) database between 2002 and 2014 and ICD-9 codes, 2614 patients were identified who were aged >=18 years and underwent EVT for PAD in the lower limb vessels. EVT was defined as angioplasty, atherectomy, and/or stenting. After excluding individuals with BMI >24, there were 807 (31%) normal-weight (BMI 19-24) patients and 1807 (69%) underweight (BMI <19) individuals. All patients in both groups were matched for baseline demographic and clinical characteristics and critical limb ischemia in a 1:1 propensity score matching analysis using the nearest neighbor method.
PURPOSE: To investigate in-hospital outcomes after endovascular therapy (EVT) in patients with severe peripheral artery disease (PAD) who had a low body mass index (BMI, kg/m<sup>2</sup>) compared to those with normal BMI.
RESULTS: Propensity score matching produced 2 groups of 685 patients that differed only in the incidence of chronic lung disease, which was more frequent in low-BMI patients (p=0.04). Patients with low BMI had a higher incidence of in-hospital mortality (4.8% vs 1.2%, p<0.001), major adverse cardiovascular events (composite of death, myocardial infarction, or stroke) (7.9% vs 4.1%, p=0.003), open bypass surgery (9.1% vs 6.0%, p=0.03), and infection (14.6% vs 10.5%, p=0.02) compared with the normal-BMI group. There was no significant difference in the incidence of vascular complications (p=0.31), major bleeding (p=0.17), major amputation (p=0.35), or acute kidney injury (p=0.09) between the low- and normal-BMI groups.
English
*Body Mass Index
*Endovascular Procedures
*Peripheral Arterial Disease/th [Therapy]
*Thinness/di [Diagnosis]
Aged
Aged, 80 and over
Comorbidity
Databases, Factual
Endovascular Procedures/ae [Adverse Effects]
Endovascular Procedures/is [Instrumentation]
Endovascular Procedures/mo [Mortality]
Female
Health Status
Hospital Mortality
Humans
Male
Middle Aged
Nutritional Status
Peripheral Arterial Disease/dg [Diagnostic Imaging]
Peripheral Arterial Disease/mo [Mortality]
Propensity Score
Retreatment
Retrospective Studies
Risk Assessment
Risk Factors
Severity of Illness Index
Stents
Thinness/mo [Mortality]
Thinness/pp [Physiopathology]
Treatment Outcome
United States
MedStar Washington Hospital Center
Medicine/Internal Medicine
Journal Article
Moussa Pacha, Homam
Soud, Mohamad
Al-Khadra Y, Alraies MC, Darmoch F, Kaki A, Mamas MA, Moussa Pacha H, Soud M
https://dx.doi.org/10.1177/1526602819839046
https://dx.doi.org/10.1177/1526602819839046
Moussa Pacha, Homam
https://orcid.org/0000-0003-4403-0941
https://orcid.org/0000-0003-4403-0941
ART
Article
0
0
0
0
Article
authcat
authcat
2019-06-21
0
30931727
30931727
2019-06-21
2019-06-21
ART
10969
10969