Universal Rapid Human Immunodeficiency Virus Screening at Delivery: A Cost-Effectiveness Analysis. - 2018

Available online from MWHC library: 1998 - present

Conclusions: Intrapartum universal rapid HIV screening to decrease MTCT appears cost-effective in populations with high HIV incidence in the United States. Objective: To determine the cost-effectiveness of universal maternal HIV screening at time of delivery to decrease mother-to-child transmission (MTCT), by comparing the cost and quality-adjusted life years (QALYs) of universal rapid HIV screening at time of delivery to two current standards of care for prenatal HIV screening in the United States. Results: The incremental cost-effectiveness ratio for universal screening was Study Design: We conducted a cost-effectiveness analysis to compare the cost and QALY of universal intrapartum rapid HIV screening with two current standards of care: (I) opt-out rapid HIV testing limited to patients without previous third-trimester screening and (II) opt-out rapid HIV testing limited to patients without any prenatal screening. We developed a decision-tree model and performed sensitivity analyses to estimate the impact of variances in QALY, estimated lifetime medical costs, HIV prevalence, and cumulative incidence.


English

1064-7449

10.1155/2018/6024698 [doi] PMC5872626 [pmc]


*HIV Infections/di [Diagnosis]
*Infectious Disease Transmission, Vertical/pc [Prevention & Control]
*Mass Screening/ec [Economics]
*Mass Screening/mt [Methods]
Adolescent
Adult
Cost-Benefit Analysis
Female
HIV Infections/ec [Economics]
Humans
Incidence
Middle Aged
Pregnancy
Prevalence
Quality-Adjusted Life Years
United States/ep [Epidemiology]
Young Adult


MedStar Health Research Institute


Journal Article