TY - BOOK AU - Cardis, Michael A AU - DeKlotz, Cynthia TI - Topical sirolimus for treatment of a venolymphatic malformation in an adolescent girl SN - 0736-8046 PY - 2018/// KW - *Immunosuppressive Agents/ad [Administration & Dosage] KW - *Sirolimus/ad [Administration & Dosage] KW - *Vascular Malformations/dt [Drug Therapy] KW - Administration, Topical KW - Adolescent KW - Female KW - Humans KW - Treatment Outcome KW - MedStar Washington Hospital Center KW - Dermatology KW - Journal Article N2 - Copyright (c) 2018 Wiley Periodicals, Inc; Sirolimus has emerged as a promising treatment for complex congenital vascular malformations but is limited because of systemic side effects. Topically compounded formulations, which have been found to be successful in the treatment of several other conditions, are a preferred drug delivery system to provide local therapy. We report a case of a venolymphatic malformation in an adolescent girl treated with topical 1% sirolimus cream leading to improvement in appearance and associated symptoms UR - https://dx.doi.org/10.1111/pde.13622 ER -