TY  - BOOK
AU  - Colice, Gene L
TI  - Effect of asthma exacerbations on health care costs among asthmatic patients with moderate and severe persistent asthma
SN  - 0091-6749
PY  - 2012///
KW  - *Asthma/ec [Economics]
KW  - *Asthma/pp [Physiopathology]
KW  - *Disease Progression
KW  - *Drug Costs
KW  - Adolescent
KW  - Adult
KW  - Asthma/ep [Epidemiology]
KW  - Child
KW  - Comorbidity
KW  - Cost of Illness
KW  - Female
KW  - Follow-Up Studies
KW  - Humans
KW  - Male
KW  - Mental Disorders/ep [Epidemiology]
KW  - Middle Aged
KW  - Pneumonia/ep [Epidemiology]
KW  - Sinusitis/ep [Epidemiology]
KW  - United States
KW  - Young Adult
KW  - MedStar Washington Hospital Center
KW  - Medicine/Pulmonary-Critical Care
KW  - Journal Article
KW  - Research Support, Non-U.S. Gov't
N1  - Available online from MWHC library: 1994 - present, Available in print through MWHC library: 1999 - 2006
N2  - BACKGROUND: Health care costs increase in patients with more severe asthma, but the effect of asthma exacerbations on costs among patients with more severe asthma has not been quantified; CONCLUSIONS: Patients with moderate/severe persistent asthma who had exacerbations had higher total and asthma-related health care costs than those without exacerbations. Moreover, controller medication use was higher in patients with exacerbations. Copyright  2012 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved; METHODS: Patients who had an asthma diagnosis (International Classification of Diseases-ninth revision-Clinical Modification code 493.x), were 12 to 64 years old, and were receiving controller therapy were identified from a large administrative claims database. Patients were categorized as having moderate/severe persistent asthma and were further evaluated for exacerbations during a 12-month exacerbation identification period. Patients with 1 or more exacerbations (asthma-related inpatient or emergency department visit or corticosteroid prescription) were matched to patients without exacerbations on demographic characteristics and asthma severity. Total and asthma-related health care costs during the 1-year study period after the exacerbation index date were calculated; OBJECTIVE: This study compared direct health care costs between patients with moderate/severe persistent asthma with and without exacerbations; RESULTS: Patients with exacerbations had significantly higher total health care costs (
UR  - http://dx.doi.org/10.1016/j.jaci.2012.01.039
ER  -