TY  - BOOK
AU  - Landy, Helain J
TI  - New laboratory procedures and Rh blood type changes in a pregnant woman
SN  - 0029-7844
KW  - *Immunologic Tests
KW  - *Pregnancy Complications, Hematologic/di [Diagnosis]
KW  - *Rh Isoimmunization/di [Diagnosis]
KW  - *Rh-Hr Blood-Group System/im [Immunology]
KW  - Adult
KW  - Female
KW  - Humans
KW  - Pregnancy
KW  - Rh-Hr Blood-Group System/ge [Genetics]
KW  - Rho(D) Immune Globulin/tu [Therapeutic Use]
KW  - MedStar Washington Hospital Center
KW  - Obstetrics and Gynecology, Maternal-Fetal Medicine
KW  - Case Reports
KW  - Journal Article
N1  - Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
N2  - BACKGROUND: A woman's candidacy for Rh immune globulin depends on whether her blood type is Rh-positive (D antigen-positive) or Rh-negative (D antigen-negative). New molecular blood-typing methods have identified variant D antigens, which may be reported as Rh-positive or Rh-negative depending on the laboratory method. We describe a case illustrating the effect of the new laboratory methods on a woman's candidacy for Rh immune globulin and present recommendations for interpreting the new test results; CASE: A 40-year-old woman presented for management of her third pregnancy. During her first pregnancy, she was typed as Rh-positive ("D") and did not receive Rh immune globulin. During her second pregnancy, she was typed as Rh-negative, in accordance with revised Rh-typing procedures. Anti-D antibody was detected. During her third pregnancy, she was genotyped as a partial D antigen, which was reported as Rh-negative; CONCLUSION: Revisions in laboratory procedures for Rh typing may present as a change in the Rh blood type of pregnant women-and as a change in their eligibility for Rh immune globulin
UR  - http://dx.doi.org/10.1097/AOG.0b013e31823f6f76
ER  -