TY  - BOOK
AU  - Nosti, Patrick A
AU  - Sokol, Andrew I
TI  - Unusual findings on cystoscopy in a patient with detrusor overactivity
SN  - 2151-8378
KW  - *Cystoscopy
KW  - *Lithium Compounds/pk [Pharmacokinetics]
KW  - *Urinary Bladder, Overactive/et [Etiology]
KW  - *Urothelium/ch [Chemistry]
KW  - Aged
KW  - Bipolar Disorder/dt [Drug Therapy]
KW  - Female
KW  - Humans
KW  - Lithium Compounds/tu [Therapeutic Use]
KW  - Urethra/ch [Chemistry]
KW  - Urinary Bladder/ch [Chemistry]
KW  - MedStar Washington Hospital Center
KW  - Obstetrics and Gynecology/Female Pelvic Medicine and Reconstructive Surgery
KW  - Case Reports
KW  - Journal Article
N2  - BACKGROUND: Chronic lithium ingestion has been shown to cause polyuria and polydipsia in 20% to 40% of patients, secondary to diabetes insipidus. However, it has not been reported to cause lithium deposition in the bladder; CASE: A 77-year-old woman presented to our clinic with complaints of urinary incontinence, urinary urgency, and nocturnal enuresis for the past 3 to 4 years. She denied polydipsia. Her medical history was significant for bipolar disorder for which she had been on lithium therapy for more than 10 years. Metallic deposition was noted in the suburothelium of a urethral biopsy by gross inspection; CONCLUSION: Suburothelial deposition of metal may act as a bladder irritant and account for this patient's overactive bladder symptoms
UR  - http://dx.doi.org/10.1097/SPV.0b013e318254f0c6
ER  -