TY  - BOOK
AU  - Antosh, Danielle D
AU  - Huang, Chun Chin
AU  - Iglesia, Cheryl B
AU  - Kudish, Bela I
AU  - Peterson, Joanna L
TI  - The effect of uterine fibroid embolization on lower urinary tract symptoms
SN  - 0937-3462
KW  - *Embolization, Therapeutic/mt [Methods]
KW  - *Leiomyoma/ep [Epidemiology]
KW  - *Leiomyoma/th [Therapy]
KW  - *Lower Urinary Tract Symptoms/ep [Epidemiology]
KW  - *Lower Urinary Tract Symptoms/th [Therapy]
KW  - Body Mass Index
KW  - Comorbidity
KW  - Female
KW  - Humans
KW  - Incidence
KW  - Middle Aged
KW  - Obesity/co [Complications]
KW  - Prospective Studies
KW  - Quality of Life
KW  - Questionnaires
KW  - Regression Analysis
KW  - Retrospective Studies
KW  - Treatment Outcome
KW  - MedStar Health Research Institute
KW  - MedStar Washington Hospital Center
KW  - Obstetrics and Gynecology/Female Pelvic Medicine and Reconstructive Surgery
KW  - Journal Article
KW  - Research Support, Non-U.S. Gov't
N1  - Available online through MWHC library: 2010 - present
N2  - CONCLUSION: Uterine fibroid embolization significantly improves LUTS and urinary-related QoL. Obesity seems to attenuate this effect; INTRODUCTION AND HYPOTHESIS: The objective was to determine the effect of uterine fibroid embolization (UFE) on lower urinary tract symptoms (LUTS) and quality of life (QoL); METHODS: This prospective study included women with symptomatic fibroids and LUTS who underwent UFE between March 2008 and May 2010. Subjects underwent pre-procedural pelvic magnetic resonance imaging (MRI) and completed the Urogenital Distress Inventory (UDI-6), Incontinence Impact Questionnaire (IIQ-7), Prolapse and Incontinence Sexual Questionnaire (PISQ-12), Uterine Fibroid Symptom Quality of Life questionnaire (UFS-QoL), and a standardized 48-h bladder diary at baseline and 3 months after the procedure. Patient Global Impression of Improvement (PGI-I) assessed post-procedural patient satisfaction. The primary outcome was subjective improvement in LUTS at 3 months, as measured by a decrease in UDI-6 score. Univariate analysis, paired t test and a stepwise regression analysis were appropriately conducted; RESULTS: Fifty-seven patients underwent UFE and completed bladder diaries and questionnaires. At 3 months after UFE, patients reported a significant decrease in UDI-6, IIQ-7, and UFS-QoL, indicating an improvement in urinary symptoms and QoL. Bladder diaries showed a significant reduction in daytime and night-time voids. No difference was found in incontinence episodes. Uterine volume, dominant fibroid size, fibroid location, and MRI-confirmed bladder compression did not affect the difference in UDI-6 scores. In a stepwise regression model, BMI had a significant impact on the 20140821 in UDI-6 score, with a decrease of 1.18 points for each 1 unit increase in BMI
UR  - http://dx.doi.org/10.1007/s00192-012-2013-7
ER  -