TY  - BOOK
AU  - Kashyap, Amit S
AU  - Kohli, Divyanshoo R
AU  - Raizon, Arnold
TI  - A prospective study evaluating emotional disturbance in subjects undergoing defecating proctography
SN  - 1007-9327
KW  - *Affective Symptoms/ep [Epidemiology]
KW  - *Colorectal Surgery/mt [Methods]
KW  - *Constipation/pp [Physiopathology]
KW  - *Constipation/px [Psychology]
KW  - *Defecography/mt [Methods]
KW  - *Gastrointestinal Diseases/pp [Physiopathology]
KW  - *Gastrointestinal Diseases/px [Psychology]
KW  - Affective Symptoms/di [Diagnosis]
KW  - Aged
KW  - Anxiety/di [Diagnosis]
KW  - Anxiety/ep [Epidemiology]
KW  - Cohort Studies
KW  - Depression/di [Diagnosis]
KW  - Depression/ep [Epidemiology]
KW  - Female
KW  - Humans
KW  - Male
KW  - Mass Screening
KW  - Middle Aged
KW  - Prevalence
KW  - Prospective Studies
KW  - Psychology
KW  - Questionnaires
KW  - Reproducibility of Results
KW  - Severity of Illness Index
KW  - Sex Offenses/px [Psychology]
KW  - Stress Disorders, Post-Traumatic/di [Diagnosis]
KW  - Stress Disorders, Post-Traumatic/ep [Epidemiology]
KW  - MedStar Washington Hospital Center
KW  - Medicine/Gastroenterology
KW  - Radiology
KW  - Journal Article
N2  - AIM: To investigate the prevalence of psychiatric illness in association with functional gastrointestinal disorders using defecating proctography (DP) and validated questionnaires; CONCLUSION: The findings of this prospective study demonstrate a significantly high degree of psychiatric ailments in patients with negative findings on DP who should be appropriately screened for a history of sexual abuse and symptoms of psychosocial distress; METHODS: We prospectively evaluated 45 subjects referred for DP using hospital anxiety and depression scale (HADS), state trait anxiety inventory (STAI), patient health questionnaire 15-item somatic symptom severity scale (PHQ-15), validated questionnaires for sexual or physical abuse; post-traumatic stress disorder questionnaire (PTSD) and ROME-III questionnaires for gastrointestinal complaints. DP results were considered negative if levator ani function was normal, rectoceles (if any) were < 4 cm and there was no evidence of intussusception, rectal prolapse, or other anatomic abnormality demonstrated. Subjects were subsequently divided into those with structural defects seen on DP (DP positive group) and those with a normal defecography study (DP negative group); RESULTS: Forty five subjects were included in the study of which 20 subjects were classified as DP negative (44.4%). There was a striking prevalence of a history of sexual abuse in DP negative group compared to the DP positive group (n = 9, 5 respectively; P = 0.036). Further, subjects in the DP negative group scored significantly higher on the HADS anxiety (6.60 + 1.00 vs 4.72 + 0.40, P = 0.04) and depression scales (5.72 + 1.00 vs 3.25 + 0.46, P = 0.01). This correlated well with significantly higher scores on the STAI state anxiety scale (42.75 + 3.16 vs 35.6 + 2.00, P = 0.027), PHQ-15 questionnaire (13.15 + 0.82 vs 10.76 + 0.97, P = 0.038) and prevalence of PTSD (20% vs 4%, P = 0.045) among DP negative subjects. There was no difference between the groups in terms of STAI trait anxiety
UR  - http://dx.doi.org/10.3748/wjg.v19.i25.3990
ER  -