TY  - BOOK
AU  - Cooper, Janelle
TI  - Ovarian reserve and subsequent assisted reproduction outcomes after methotrexate therapy for ectopic pregnancy or pregnancy of unknown location
SN  - 0015-0282
KW  - *Methotrexate/tu [Therapeutic Use]
KW  - *Oocyte Retrieval/td [Trends]
KW  - *Pregnancy, Ectopic/dt [Drug Therapy]
KW  - *Pregnancy, Ectopic/su [Surgery]
KW  - *Reproductive Techniques, Assisted/td [Trends]
KW  - Adult
KW  - Cohort Studies
KW  - Female
KW  - Humans
KW  - Pregnancy
KW  - Pregnancy, Ectopic/di [Diagnosis]
KW  - Retrospective Studies
KW  - Treatment Outcome
KW  - MedStar Washington Hospital Center
KW  - Obstetrics and Gynecology
KW  - Journal Article
KW  - Research Support, N.I.H., Extramural
N1  - Available online from MWHC library: 1997 - present, Available in print through MWHC library:1999-2007
N2  - CONCLUSION(S): Ovarian reserve and subsequent ART cycle outcomes were reassuring after methotrexate or surgical management of ectopic pregnancy. No adverse impact of methotrexate was detected in this large fertility cohort as has been previously described elsewhere. Published by Elsevier Inc; DESIGN: Retrospective cohort study; INTERVENTION(S): None; MAIN OUTCOME MEASURE(S): Follicle-stimulating hormone (FSH), antral follicle count (AFC), and oocyte yield compared between women treated with methotrexate or surgery, with secondary outcomes of clinical pregnancy and live birth; OBJECTIVE: To assess ovarian reserve after methotrexate treatment for ectopic pregnancy or pregnancy of unknown location after assisted reproductive technology (ART); PATIENT(S): Women receiving methotrexate or surgery after ART; RESULT(S): There were 153 patients in the methotrexate group and 36 patients in the surgery group. Neither group demonstrated differences in ovarian reserve or oocyte yield in a comparison of the before and after treatment values. The 20140821 in ovarian reserve and oocyte yield after treatment were similar between the two groups. The number of doses of methotrexate was not correlated with 140821s in ovarian reserve, indicating no dose-dependent effect. Time between treatment and repeat ART was not correlated with outcomes. Live birth in subsequent cycles was similar in the two groups; SETTING: Large ART practice
UR  - http://dx.doi.org/10.1016/j.fertnstert.2013.10.027
ER  -