TY - BOOK AU - Mete, Mihriye TI - Effect of propofol anesthesia on force application during colonoscopy SN - 0016-5107 KW - *Anesthetics, Intravenous/pd [Pharmacology] KW - *Colonoscopy/mt [Methods] KW - *Propofol/pd [Pharmacology] KW - Cohort Studies KW - Colonoscopes KW - Deep Sedation KW - Equipment Design KW - Female KW - Humans KW - Male KW - Mechanical Processes KW - Middle Aged KW - MedStar Health Research Institute KW - Comparative Study KW - Journal Article KW - Observational Study KW - Research Support, N.I.H., Extramural N1 - Available online from MWHC library: 1994 - present, Available in print through MWHC library: 1999 - 2006 N2 - BACKGROUND: Sedation is frequently used during colonoscopy to control patient discomfort and pain. Propofol is associated with a deeper level of sedation than is a combination of a narcotic and sedative hypnotic and, therefore, may be associated with an increase in force applied to the colonoscope to advance and withdraw the instrument; CONCLUSIONS: Propofol sedation is associated with a decrease in examination time and an increase in axial and radial forces used to advance the colonoscope.Copyright � 2014. Published by Mosby, Inc; DESIGN: An observational cohort study of 13 expert and 12 trainee endoscopists performing colonoscopy in 114 patients. Forces were measured by using the colonoscopy force monitor, which is a wireless, handheld device that attaches to the insertion tube of the colonoscope; LIMITATIONS: Small study, observational design, nonrandomized distribution of sedation type and experience level, different instrument type and effect of prototype device on insertion tube manipulation; MAIN OUTCOME MEASUREMENTS: Axial and radial forces and examination time; OBJECTIVE: To compare force application to the colonoscope insertion tube during propofol anesthesia and moderate sedation; PATIENTS: Patients undergoing routine screening or diagnostic colonoscopy with complete segment force recordings; RESULTS: Axial and radial forces increase and examination time decreases significantly when propofol is used as the method of anesthesia; SETTING: Community ambulatory surgery center and academic gastroenterology training programs UR - http://dx.doi.org/10.1016/j.gie.2013.12.002 ER -