TY  - BOOK
AU  - Boyle, Lisa M
AU  - Burman, Kenneth D
AU  - Carroll, Nancy M
AU  - Kushchayeva, Yevgeniya
AU  - Van Nostrand, Douglas
AU  - Wexler, Jason
TI  - Current treatment modalities for spinal metastases secondary to thyroid carcinoma. [Review]
SN  - 1050-7256
KW  - *Carcinoma/sc [Secondary]
KW  - *Carcinoma/th [Therapy]
KW  - *Spinal Neoplasms/sc [Secondary]
KW  - *Spinal Neoplasms/th [Therapy]
KW  - *Thyroid Neoplasms/pa [Pathology]
KW  - Algorithms
KW  - Carcinoma/mo [Mortality]
KW  - Critical Pathways
KW  - Humans
KW  - Patient Selection
KW  - Quality of Life
KW  - Spinal Neoplasms/mo [Mortality]
KW  - Thyroid Neoplasms/mo [Mortality]
KW  - Treatment Outcome
KW  - MedStar Washington Hospital Center
KW  - Medicine/Endocrinology
KW  - Medicine/Nuclear Medicine
KW  - Surgery
KW  - Surgery/General Surgery
KW  - Journal Article
KW  - Review
N1  - Available online from MWHC library: August 2000 - present, Available in print through MWHC library: 1999 - 2006
N2  - BACKGROUND: The spine is the most common site of bone metastases due to thyroid cancer, which develop in more than 3% of patients with well-differentiated thyroid cancer. Nearly half of patients with bone metastases from thyroid cancer develop vertebral metastases. Spinal metastases are associated with significantly reduced quality of life due to pain, neurological deficit, and increased mortality; CONCLUSIONS: The introduction of novel and improved techniques for the treatment of spinal metastases has created the opportunity to significantly improve control of metastatic tumor growth and the quality of life for the patients with spinal metastases from thyroid cancer. In order for these options to be effectively used, a multidisciplinary approach must be applied in the management of the patients with thyroid spinal metastases; SUMMARY: Treatment options for patients with thyroid spinal metastases include radioiodine therapy, pharmacologic therapy, and surgical treatments, with recent advances in radiosurgery and minimally invasive spinal surgery as well. Therapeutic interventions require a multidisciplinary approach and aim to control pain, preserve or improve neurologic function, optimize local tumor control, and improve quality of life. We have proposed a three-tiered approach to the management and practical algorithms for patients with spinal metastases from thyroid carcinoma
UR  - http://dx.doi.org/10.1089/thy.2013.0634
ER  -