Developing trends in the intestinal transplant waitlist.

Available online from MWHC library: May 2001 - present

The United Network for Organ Sharing database was examined for trends in the intestinal transplant (ITx) waitlist from 1993 to 2012, dividing into listings for isolated ITx versus liver-intestine transplant (L-ITx). Registrants added to the waitlist increased from 59/year in 1993 to 317/year in 2006, then declined to 124/year in 2012; Spline modeling showed a significant change in the trend in 2006, p<0.001. The largest group of registrants, <1year of age, determined the trend for the entire population; other pediatric age groups remained stable, adult registrants increased until 2012. The largest proportion of new registrants were for L-ITx, compared to isolated ITx; the change in the trend in 2006 for L-ITx was highly significant, p<0.001, but not isolated ITx, p=0.270. New registrants for L-ITx, <1year of age, had the greatest increase and decrease. New registrants for isolated ITx remained constant in all pediatric age groups. Waitlist mortality increased to a peak around 2002, highest for L-ITx, in patients <1year of age and adults. Deaths among all pediatric age groups awaiting L-ITx have decreased; adult L-ITx deaths have dropped less dramatically. Improved care of infants with intestinal failure has led to reduced referrals for L-ITx. � Copyright 2014 The American Society of Transplantation and the American Society of Transplant Surgeons.


English

1600-6135


*Intestines/tr [Transplantation]
*Mortality/td [Trends]
*Organ Transplantation/mo [Mortality]
*Organ Transplantation/sn [Statistics & Numerical Data]
*Tissue and Organ Procurement/sn [Statistics & Numerical Data]
*Waiting Lists/mo [Mortality]
Adolescent
Adult
Age Factors
Child
Child, Preschool
Female
Follow-Up Studies
Humans
Infant
Infant, Newborn
Male
Prognosis
Survival Rate
Young Adult


MedStar Health Research Institute
MedStar Washington Hospital Center


Surgery/Transplantation


Journal Article
Research Support, U.S. Gov't, P.H.S.