TY - BOOK AU - Desai, Chirag S AU - Desale, Sameer Y AU - Fishbein, Thomas M AU - Girlanda, Raffaele AU - Hawksworth, Jason S AU - Kaufman, Stuart S AU - Matsumoto, Cal S AU - Mete, Mihriye TI - Developing trends in the intestinal transplant waitlist SN - 1600-6135 KW - *Intestines/tr [Transplantation] KW - *Mortality/td [Trends] KW - *Organ Transplantation/mo [Mortality] KW - *Organ Transplantation/sn [Statistics & Numerical Data] KW - *Tissue and Organ Procurement/sn [Statistics & Numerical Data] KW - *Waiting Lists/mo [Mortality] KW - Adolescent KW - Adult KW - Age Factors KW - Child KW - Child, Preschool KW - Female KW - Follow-Up Studies KW - Humans KW - Infant KW - Infant, Newborn KW - Male KW - Prognosis KW - Survival Rate KW - Young Adult KW - MedStar Health Research Institute KW - MedStar Washington Hospital Center KW - Surgery/Transplantation KW - Journal Article KW - Research Support, U.S. Gov't, P.H.S N1 - Available online from MWHC library: May 2001 - present N2 - The United Network for Organ Sharing database was examined for trends in the intestinal transplant (ITx) waitlist from 1993 to 2012, dividing into listings for isolated ITx versus liver-intestine transplant (L-ITx). Registrants added to the waitlist increased from 59/year in 1993 to 317/year in 2006, then declined to 124/year in 2012; Spline modeling showed a significant change in the trend in 2006, p<0.001. The largest group of registrants, <1year of age, determined the trend for the entire population; other pediatric age groups remained stable, adult registrants increased until 2012. The largest proportion of new registrants were for L-ITx, compared to isolated ITx; the change in the trend in 2006 for L-ITx was highly significant, p<0.001, but not isolated ITx, p=0.270. New registrants for L-ITx, <1year of age, had the greatest increase and decrease. New registrants for isolated ITx remained constant in all pediatric age groups. Waitlist mortality increased to a peak around 2002, highest for L-ITx, in patients <1year of age and adults. Deaths among all pediatric age groups awaiting L-ITx have decreased; adult L-ITx deaths have dropped less dramatically. Improved care of infants with intestinal failure has led to reduced referrals for L-ITx. � Copyright 2014 The American Society of Transplantation and the American Society of Transplant Surgeons UR - http://dx.doi.org/10.1111/ajt.12919 ER -