TY  - BOOK
AU  - Nandyala, Arathi 
AU  - Shah, Tulsi 
TI  - Hemiplegic Migraine. [Review]
SN  - 1528-4042
PY  - 2023///
KW  - *Epilepsy
KW  - *Migraine Disorders
KW  - *Migraine with Aura
KW  - Epilepsy/di [Diagnosis]
KW  - Hemiplegia/co [Complications]
KW  - Hemiplegia/di [Diagnosis]
KW  - Humans
KW  - Migraine Disorders/di [Diagnosis]
KW  - Migraine Disorders/ep [Epidemiology]
KW  - Migraine Disorders/ge [Genetics]
KW  - Migraine with Aura/di [Diagnosis]
KW  - Migraine with Aura/ep [Epidemiology]
KW  - Migraine with Aura/ge [Genetics]
KW  - Neurons
KW  - Automated
KW  - MedStar Georgetown University Hospital/MedStar Washington Hospital Center
KW  - Neurology Residency
KW  - Journal Article
KW  - Review
N2  - PURPOSE OF REVIEW: In this article, we review recent updates to the epidemiology, diagnostic testing, genetics, pathophysiology, and management of hemiplegic migraine; RECENT FINDINGS: While three genes have been historically associated with hemiplegic migraine, recent studies suggest two additional genes may also be implicated including PPRT2 and SLC1A3. Hemiplegic migraine is a severe subset of migraine with aura with symptoms including reversible hemiparesis in addition to other aura symptoms such as visual, sensory, or speech. The exact pathophysiology of hemiplegic migraine is not clear, but it is thought that this phenomenon is due to neuronal and glial depolarization causing cortical spreading depression. Due to the severity of presentation as well as the numerous mimickers, it is important to know a comprehensive differential and work-up. Given the low prevalence of the disease, most studies regarding treatment are limited to case studies. There is still an important need for further and larger studies regarding management of these cases. Copyright © 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature
UR  - https://dx.doi.org/10.1007/s11910-023-01277-z
ER  -