The impact of pre-pregnancy body mass index on the risk of gestational diabetes. 

 -  2012 
<br/><br/>Available online through MWHC library: 2013 to the present 
<br/><br/> CONCLUSIONS: GDM is a multifactorial disorder and pre-pregnancy BMI plays an important role in that risk. Modest 130912s in pre-pregnancy BMI may decrease the risk of GDM substantially.  METHODS: We performed a case control study using data collected in The Consortium on Safe Labor database. The association between BMI and GDM was evaluated both using BMI weight categories adopted by the National Institute of Health, and separately using BMI as a continuous variable. Multiple logistic regression analyses were used to evaluate the effects of BMI, age, ethnicity, parity, chronic hypertension and antenatal steroid use on the risk of GDM. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to approximate relative risks of GDM. A p value of <0.05 was considered significant.  OBJECTIVE: To evaluate the effect of pre-pregnancy body mass index (BMI) on the risk of developing gestational diabetes mellitus (GDM) in a large unselected population.  RESULTS: After controlling for other factors, the risk of GDM increased with an increasing BMI across all weight categories. For each 1 kg/m(2) increase of BMI the OR of developing GDM was 1.08 (95% CI 1.08-1.09) and for each 5 kg/m(2) increase, the OR was 1.48 (95% CI 1.45-1.51). 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>1476-4954 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*Body Mass Index<br/>*Diabetes, Gestational/ep [Epidemiology]<br/>*Preconception Care<br/>Case-Control Studies<br/>Diabetes, Gestational/eh [Ethnology]<br/>Ethnic Groups<br/>Female<br/>Humans<br/>Hypertension<br/>Logistic Models<br/>National Institutes of Health (U.S.)<br/>Obesity/co [Complications]<br/>Obesity/di [Diagnosis]<br/>Odds Ratio<br/>Parity<br/>Pregnancy<br/>Pregnancy Complications<br/>Risk Factors<br/>United States
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar Health Research Institute<br/>MedStar Washington Hospital Center
<br/><br/><label>Index Terms--Occupation: </label><br/>Obstetrics and Gynecology/Maternal-Fetal Medicine
<br/><br/><label>Index Terms--Function: </label><br/>Journal Article<br/>Research Support, N.I.H., Extramural<br/>Research Support, Non-U.S. Gov't