Typical migraine or ophthalmologic emergency?. - 2012

Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006

We describe the case of a 47-year-old woman who came to the emergency department (ED) complaining of worse than typical migraine headache and blurry vision after recently doubling the dose of topiramate earlier that day. After complete neurologic and ophthalmologic evaluation, she was found to have elevated intraocular pressures and was diagnosed with topiramate-induced bilateral acute angleclosure glaucoma, which is a rare side effect of this commonly prescribed medication. She was treated with timolol, brimonide, and prednisolone drops to reduce intraocular pressure as well as cessation of topiramate and was discharged home. This report briefly discusses the clinical history, appropriate evaluation, differential diagnosis, and approach to secondary acute angle-closure glaucoma in the ED.


English

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*Glaucoma, Angle-Closure/di [Diagnosis]
*Migraine Disorders/di [Diagnosis]
Emergency Service, Hospital
Female
Fructose/aa [Analogs & Derivatives]
Fructose/ae [Adverse Effects]
Fructose/tu [Therapeutic Use]
Glaucoma, Angle-Closure/ci [Chemically Induced]
Humans
Intraocular Pressure/de [Drug Effects]
Middle Aged
Migraine Disorders/dt [Drug Therapy]
Neuroprotective Agents/ae [Adverse Effects]
Neuroprotective Agents/tu [Therapeutic Use]


MedStar Washington Hospital Center


Emergency Medicine


Case Reports
Journal Article