TY  - BOOK
AU  - Walitt, Brian
TI  - Predictors of 130912 in pain and physical functioning among post-menopausal women with recurrent pain conditions in the women's health initiative observational cohort
SN  - 1526-5900
PY  - 2012///
KW  - *Health Status
KW  - *Motor Activity/ph [Physiology]
KW  - *Pain/ep [Epidemiology]
KW  - *Pain/pp [Physiopathology]
KW  - *Women's Health
KW  - Aged
KW  - Body Mass Index
KW  - Cohort Studies
KW  - Depression
KW  - Female
KW  - Humans
KW  - Logistic Models
KW  - Longitudinal Studies
KW  - Middle Aged
KW  - Observation
KW  - Pain/dt [Drug Therapy]
KW  - Pain/px [Psychology]
KW  - Postmenopause
KW  - Predictive Value of Tests
KW  - Quality of Life
KW  - Randomized Controlled Trials as Topic
KW  - MedStar Washington Hospital Center
KW  - Medicine/Rheumatology
KW  - Journal Article
KW  - Research Support, N.I.H., Extramural
KW  - Research Support, U.S. Gov't, Non-P.H.S
N1  - Available online from MWHC library: 2000 - 2008
N2  - Pain complaints are commonly reported symptoms among postmenopausal women and can have significant effects on health-related quality of life. We sought to identify medical and psychosocial factors that predict 130912s in pain and overall physical functioning over a 3-year period among postmenopausal women with recurrent pain conditions. We examined data from postmenopausal women age 50 to 79 with recurrent pain conditions (low back pain, neck pain, headache or migraines, or joint pain or stiffness) over a 3-year period using the Women's Health Initiative Observational Study Cohort (N = 67,963). Multinomial logistic regression models controlling for demographic and clinical characteristics were used to identify baseline predictors of 130912 in the SF-36 subscales for pain and physical functioning between baseline and 3-year follow-up. Body mass index (BMI) was associated with worsening of pain (OR [95% CI] 1.54 [1.45-1.63] for BMI >=30) and physical functioning (1.83 [1.71-1.95] for BMI >=30). A higher reported number of nonpain symptoms, higher medical comorbidity, and a positive screen for depression (1.13 [1.05-1.22] for worsened pain) were also associated with worsening of pain and physical functioning. Baseline prescription opioid use was also associated with lack of improvement in pain (OR .42, 95% CI .36-.49) and with worsened physical functioning (1.25 [1.04-1.51]). PERSPECTIVE: This study presents prospective data on 130912 in pain and physical functioning in postmenopausal women over a 3-year period. Our results suggest depression, nonpain physical symptoms, obesity, and possibly opioid treatment are associated with worse long-term pain outcomes in this population. Copyright  2012 American Pain Society. Published by Elsevier Inc. All rights reserved
UR  - http://dx.doi.org/10.1016/j.jpain.2011.10.007
ER  -