TY - BOOK AU - Magalhaes, Marco A AU - Minha, Sa'ar TI - Characteristics and management of patients with acute coronary syndrome and normal or non-significant coronary artery disease: results from Acute Coronary Syndrome Israeli Survey (ACSIS) 2004-2010 SN - 1042-3931 PY - 2014/// KW - *Acute Coronary Syndrome KW - *Coronary Artery Disease/pp [Physiopathology] KW - *Disease Management KW - Acute Coronary Syndrome/di [Diagnosis] KW - Acute Coronary Syndrome/et [Etiology] KW - Acute Coronary Syndrome/mo [Mortality] KW - Acute Coronary Syndrome/pp [Physiopathology] KW - Acute Coronary Syndrome/th [Therapy] KW - Age Factors KW - Aged KW - Coronary Angiography/mt [Methods] KW - Coronary Artery Disease/co [Complications] KW - Coronary Artery Disease/di [Diagnosis] KW - Female KW - Health Surveys KW - Hospital Mortality KW - Hospitalization/sn [Statistics & Numerical Data] KW - Humans KW - Israel/ep [Epidemiology] KW - Male KW - Middle Aged KW - Risk Factors KW - Sex Factors KW - MedStar Heart & Vascular Institute KW - Journal Article N1 - Available online from MWHC library: 2001 - present, Available in print through MWHC library: 2003 - 2008 N2 - BACKGROUND: An important subset of patients presenting with acute coronary syndrome (ACS) are found to have either normal coronaries (NCs) or non-obstructive coronary artery disease (NOCAD; lumen diameter narrowing <50%); CONCLUSIONS: In a real-world practice of ACS, underutilization of evidence-based medications in patients with NC or NOCAD was observed. Nonetheless, its prognostic significance is still unknown and must be explored in larger patient cohorts; METHODS: The Acute Coronary Syndrome Israeli Survey (ACSIS) database was utilized to compare the characteristics and therapeutic approach for patients who underwent angiography for ACS and had either NC (n = 84; 2%), NOCAD (n = 79; 2%), or obstructive coronary artery disease (OCAD; n = 3523; 96%); OBJECTIVES: To explore the characteristics and management strategies in this population in a real-world setting; RESULTS: Baseline characteristics were comparable, save for a younger age and a higher proportion of females in the NC group (P<.001 for both). Prior to admission, chronic anticoagulant therapy was more frequently used in the NC vs. the OCAD group (4.8% vs. 1.6%, respectively; P=.02). Recommended ACS evidence-based medications, both in-hospital and at discharge, were less frequently prescribed to patients with NC or NOCAD ER -