A 2013 European survey of clinical practice patterns in the management of Graves' disease. 

 -  2016 
<br/><br/> CONCLUSIONS: Significant changes in clinical practice patterns in Europe were noted compared to the previous European survey, as well as persisting differences in diagnosis and therapy between Europe and North America.Copyright © 2015 John Wiley & Sons Ltd.  DESIGN: Members of the European Thyroid Association (ETA) were asked to participate in a survey on management of GD, using the same questionnaire of a recent American survey.  OBJECTIVE: Management of Graves' disease (GD) in Europe was published in 1987. Aim of this survey was to provide an update on clinical practice in Europe, and to compare it with a 2011 American survey.  RESULTS: A total of 147 ETA members participated. In addition to serum TSH and free T4 assays, most respondents would request TSH-receptor autoantibody (TRAb) measurement (85.6%) and thyroid ultrasound (70.6%) to confirm aetiology, while isotopic studies were selected by 37.7%. Antithyroid drug (ATD) therapy was the preferred first-line treatment (83.8%). Compared to the previous European survey, Europeans currently more frequently use TRAb measurement and thyroid ultrasound for diagnosis and evaluation, but first-line treatment remains ATDs in a similar percentage of respondents. Current clinical practice patterns differ from those in North America, where isotopic studies are more frequently used, and radioiodine (RAI) still is first-line treatment. When RAI treatment is selected in the presence of mild Graves' orbitopathy and/or associated risk factors for its occurrence/exacerbation, steroid prophylaxis is frequently used. The preferred ATD in pregnancy is propylthiouracil in the first trimester and methimazole in the second and third trimesters, similar to North America. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>0300-0664 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*Graves Disease/di [Diagnosis]<br/>*Graves Disease/dt [Drug Therapy]<br/>*Practice Patterns, Physicians'/sn [Statistics & Numerical Data]<br/>*Surveys and Questionnaires<br/>Antithyroid Agents/tu [Therapeutic Use]<br/>Autoantibodies/bl [Blood]<br/>Autoantibodies/im [Immunology]<br/>Europe<br/>Female<br/>Graves Disease/bl [Blood]<br/>Humans<br/>Methimazole/tu [Therapeutic Use]<br/>North America<br/>Pregnancy<br/>Pregnancy Complications/bl [Blood]<br/>Pregnancy Complications/di [Diagnosis]<br/>Pregnancy Complications/dt [Drug Therapy]<br/>Propylthiouracil/tu [Therapeutic Use]<br/>Receptors, Thyrotropin/im [Immunology]<br/>Thyrotropin/bl [Blood]<br/>Thyroxine/bl [Blood]
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar Washington Hospital Center
<br/><br/><label>Index Terms--Occupation: </label><br/>Medicine/Endocrinology
<br/><br/><label>Index Terms--Function: </label><br/>Journal Article