TY  - BOOK
AU  - Al-Refaie, Waddah B
TI  - Approach to the surgical management of resectable gastric cancer. [Review]
SN  - 1543-0790
PY  - 2016///
KW  - *Stomach Neoplasms/di [Diagnosis]
KW  - *Stomach Neoplasms/su [Surgery]
KW  - Biomarkers, Tumor
KW  - Clinical Decision-Making
KW  - Clinical Trials as Topic
KW  - Combined Modality Therapy
KW  - Disease Management
KW  - Gastrectomy/mt [Methods]
KW  - Humans
KW  - Incidence
KW  - Lymph Node Excision
KW  - Neoplasm Staging/mt [Methods]
KW  - Palliative Care
KW  - Preoperative Care
KW  - Stomach Neoplasms/ep [Epidemiology]
KW  - Stomach Neoplasms/mo [Mortality]
KW  - Treatment Outcome
KW  - MedStar Health Research Institute
KW  - Journal Article
KW  - Review
N2  - The rates of gastric cancer, which is the third leading cause of cancer-related deaths worldwide, vary depending on geographic location. Margin-negative gastrectomy and adequate lymphadenectomy (removal of >15 lymph nodes) are the cornerstones of multimodal treatment for operable gastric cancer. Diagnostic laparoscopy should be included in the armamentarium for newly diagnosed gastric cancer in order to overcome the limitations of cross-sectional imaging in identifying sub-radiographic hepatic or peritoneal metastases. The benefit of surgical therapy is enhanced by at least 13% when it is integrated with multimodal therapy: either surgery followed by adjuvant chemoradiotherapy or surgery with perioperative systemic therapy. This multidisciplinary approach to treatment will continue to be an evolving paradigm, especially with the emergence of systemic and targeted therapies
ER  -