TY  - BOOK
AU  - Baker, Nevin C
AU  - Chen, Fang
AU  - Escarcega, Ricardo O
AU  - Lipinski, Michael J
AU  - Magalhaes, Marco A
AU  - Minha, Sa'ar
AU  - Pichard, Augusto D
AU  - Satler, Lowell F
AU  - Torguson, Rebecca
AU  - Waksman, Ron
TI  - Does the disparity in baseline characteristics of patients undergoing transcatheter aortic valve replacement with 23 mm vs. 26 mm valves impact clinical outcome?
SN  - 1522-1946
PY  - 2016///
KW  - *Aortic Valve Stenosis/su [Surgery]
KW  - *Aortic Valve/su [Surgery]
KW  - *Transcatheter Aortic Valve Replacement/mt [Methods]
KW  - Aged, 80 and over
KW  - Aortic Valve Stenosis/di [Diagnosis]
KW  - Aortic Valve/dg [Diagnostic Imaging]
KW  - Female
KW  - Follow-Up Studies
KW  - Humans
KW  - Male
KW  - Prosthesis Design
KW  - Retrospective Studies
KW  - Severity of Illness Index
KW  - Tomography, X-Ray Computed
KW  - Treatment Outcome
KW  - MedStar Heart & Vascular Institute
KW  - Journal Article
N1  - Available online from MWHC library: 1996 - present, Available in print through MWHC library: 1996 - 2006
N2  - BACKGROUND: Transcatheter aortic valve replacement (TAVR) is currently an approved therapy for patients with severe aortic stenosis who are considered inoperable or are at high risk; CONCLUSION: Patients undergoing TAVR with 23 and 26 mm valves have similar clinical outcomes despite significant differences in baseline characteristics. © 2015 Wiley Periodicals, Inc; Copyright © 2015 Wiley Periodicals, Inc; METHODS: We retrospectively examined baseline characteristics and outcomes of patients receiving a 23 mm (n=132) vs. 26 mm valve (n=81) via the transfemoral approach; OBJECTIVES: We sought to identify if baseline characteristic differences in patients who receive a 23 mm vs. 26 mm valve impact clinical outcomes; RESULTS: Gender (P<0.01), previous coronary artery bypass surgery (P<0.01), history of atrial fibrillation (P=0.04), and mean Society of Thoracic Surgeons (STS) score (P<0.01) were significantly different between groups. There were no significant differences in the rates of minor/major vascular complications (2.2 vs. 3.7%, P=0.68 and 13.0 vs. 12.3%, P=0.89, respectively). Bleeding complications were also comparable (major bleed 2.3 vs. 1%, P >0.99, minor bleed 19.0 vs. 22.0%, P=0.67 and life threatening bleed 7.0 vs. 5.0%, P=0.77). In-hospital death (6.0 vs. 5.0%, P >0.99), 30-day all-cause death (7.6 vs. 6.2%, P=0.69), and all-cause death at 1 year (17.4 vs. 25.9%, P=0.13) were also similar between groups. Gender, valve size, previous coronary bypass surgery and atrial fibrillation were not independently associated with mortality; however, on multivariate analysis STS score was (HR 1.11; 95% CI 1.02-1.19; P=0.01)
UR  - https://dx.doi.org/10.1002/ccd.25967
ER  -