TY  - BOOK
AU  - Baker, Nevin C
AU  - Ben-Dor, Itsik
AU  - Bernardo, Nelson L
AU  - Escarcega, Ricardo O
AU  - Kiramijyan, Starkis
AU  - Koifman, Edward
AU  - Magalhaes, Marco A
AU  - Okubagzi, Petros
AU  - Pichard, Augusto D
AU  - Satler, Lowell F
AU  - Torguson, Rebecca
AU  - Waksman, Ron
TI  - The adjunctive use of Angio-Seal in femoral vascular closure following percutaneous transcatheter aortic valve replacement
SN  - 1774-024X
PY  - 2016///
KW  - *Aortic Valve Stenosis/su [Surgery]
KW  - *Aortic Valve/su [Surgery]
KW  - *Femoral Artery/su [Surgery]
KW  - *Heart Valve Prosthesis Implantation
KW  - *Transcatheter Aortic Valve Replacement
KW  - Aged
KW  - Aged, 80 and over
KW  - Cardiac Catheterization/mt [Methods]
KW  - Female
KW  - Heart Valve Prosthesis Implantation/mt [Methods]
KW  - Heart Valve Prosthesis/ae [Adverse Effects]
KW  - Hemostatic Techniques/ae [Adverse Effects]
KW  - Humans
KW  - Male
KW  - Retrospective Studies
KW  - Transcatheter Aortic Valve Replacement/mt [Methods]
KW  - Treatment Outcome
KW  - MedStar Heart & Vascular Institute
KW  - Journal Article
N2  - AIMS: The objective of this study was to describe and evaluate the adjunctive technique of Angio-Seal (AS) use to augment the dual Perclose ProGlide (PP) in achieving haemostasis in patients undergoing transfemoral percutaneous transcatheter aortic valve replacement (TAVR); CONCLUSIONS: The adjunctive Angio-Seal technique to augment the dual PP pre-close strategy for patients undergoing percutaneous femoral closure following TAVR is feasible and safe and may be considered as a bail-out or an alternative strategy when the dual PP closure technique fails to obtain complete haemostasis; METHODS AND RESULTS: All patients who underwent TAVR from May 2007 to January 2015 via a planned transfemoral percutaneous approach with a dual PP pre-close strategy were retrospectively analysed. This cohort was divided into two groups: dual PP versus dual PP with adjunctive AS (PP+AS) use based on the specific status of intraprocedural haemostasis. The baseline and procedural characteristics and in-hospital outcomes were prospectively collected and retrospectively compared. Overall, a total of 387 consecutive patients (55% male, mean age 83 years) with dual PP (n=179) vs. dual PP+AS (n=208) were evaluated. There were no statistically significant differences between the dual PP vs. dual PP+AS groups with regard to the in-hospital Valve Academic Research Consortium-2 (VARC-2) primary endpoints of major vascular complications (8.0% vs. 6.6%, p=0.592), minor vascular complications (18.4% vs. 13.7%, p=0.218), life-threatening or disabling bleeding (5.1% vs. 3.0%, p=0.291), major bleeding (1.7% vs. 1.5%, p=1.000), and minor bleeding (14.4% vs. 10.6%, p=0.271)
UR  - https://dx.doi.org/10.4244/EIJV12I1A16
ER  -