TY - BOOK AU - Najjar, Samer S TI - The Systematic Evaluation of Identifying the Infarct Related Artery Utilizing Cardiac Magnetic Resonance in Patients Presenting with ST-Elevation Myocardial Infarction SN - 1932-6203 PY - 2017/// KW - *Electrocardiography KW - *Magnetic Resonance Imaging KW - *Myocardial Infarction/di [Diagnosis] KW - *Myocardial Infarction/pp [Physiopathology] KW - Aged KW - Coronary Angiography KW - Humans KW - Image Processing, Computer-Assisted KW - Magnetic Resonance Imaging/mt [Methods] KW - Middle Aged KW - Multicenter Studies as Topic KW - Myocardial Infarction/co [Complications] KW - Myocardial Infarction/th [Therapy] KW - Percutaneous Coronary Intervention KW - Randomized Controlled Trials as Topic KW - MedStar Heart & Vascular Institute KW - Journal Article N1 - Available online through MWHC library: 2006 - present N2 - BACKGROUND: Identification of the infarct-related artery (IRA) in patients with STEMI using coronary angiography (CA) is often based on the ECG and can be challenging in patients with severe multi-vessel disease. The current study aimed to determine how often percutaneous intervention (PCI) is performed in a coronary artery different from the artery supplying the territory of acute infarction on cardiac magnetic resonance imaging (CMR); CONCLUSIONS: In this select population of patients, the identification of the IRA by CA was incorrect in 4% of patients presenting with STEMI. Four patients with a mismatch had an acute infarction in more than one coronary artery territory on CMR. The role of CMR in patients presenting with STEMI with multi-vessel disease on CA deserves further investigation; METHODS: We evaluated 113 patients from the Reduction of infarct Expansion and Ventricular remodeling with Erythropoetin After Large myocardial infarction (REVEAL) trial, who underwent CMR within 4+/-2 days of revascularization. Blinded reviewers interpreted CA to determine the IRA and CMR to determine the location of infarction on a 17-segment model. In patients with multiple infarcts on CMR, acuity was determined with T2-weighted imaging and/or evidence of microvascular obstruction; RESULTS: A total of 5 (4%) patients were found to have a mismatch between the IRA identified on CMR and CA. In 4/5 cases, there were multiple infarcts noted on CMR. Thirteen patients (11.5%) had multiple infarcts in separate territories on CMR with 4 patients (3.5%) having multiple acute infarcts and 9 patients (8%) having both acute and chronic infarcts UR - https://dx.doi.org/10.1371/journal.pone.0169108 ER -