TY  - BOOK
AU  - Dahagam, Chanukya R
AU  - Goud, Aditya
TI  - Invasive Cardiac Lipoma: a case report and review of literature. [Review]
SN  - 1471-2261
PY  - 2017///
KW  - *Heart Atria/dg [Diagnostic Imaging]
KW  - *Heart Neoplasms/dg [Diagnostic Imaging]
KW  - *Lipoma/dg [Diagnostic Imaging]
KW  - *Magnetic Resonance Imaging
KW  - Adult
KW  - Biopsy
KW  - Diagnosis, Differential
KW  - Dyspnea/et [Etiology]
KW  - Echocardiography
KW  - Heart Atria/pa [Pathology]
KW  - Heart Atria/su [Surgery]
KW  - Heart Neoplasms/co [Complications]
KW  - Heart Neoplasms/pa [Pathology]
KW  - Heart Neoplasms/su [Surgery]
KW  - Humans
KW  - Lipoma/co [Complications]
KW  - Lipoma/pa [Pathology]
KW  - Lipoma/su [Surgery]
KW  - Male
KW  - Neoplasm Invasiveness
KW  - Predictive Value of Tests
KW  - Treatment Outcome
KW  - Tumor Burden
KW  - MedStar Franklin Square Medical Center
KW  - Medicine
KW  - Case Reports
KW  - Journal Article
KW  - Review
N1  - Available online from MWHC library: 2001 - present
N2  - BACKGROUND: Cardiac lipomas are rare benign tumors of the heart. They are usually asymptomatic and are thus most often diagnosed on autopsies. Symptoms, when present, depend upon the location within the heart. Typical locations are the endocardium of the right atrium and the left ventricle. Diagnostic modality of choice is cardiac MRI. Treatment guidelines have not yet been established due to the very low prevalence of these tumors and are thus guided by the patient's symptomatology; CASE PRESENTATION: We describe a case of an invasive cardiac lipoma, wherein the initial symptom of the patient was shortness of breath. Although the echocardiogram visualized the tumor in the right atrium, a cardiac MRI was performed for better tissue characterization. The MRI revealed a large, fat containing, septated mass in the right atrium with invasion into the inter-atrial septum and inferior cavoatrial junction. There was also invasion of the coronary sinus along the inferior and left lateral aspect of the posterior atrioventricular groove. Although the mass appeared to represent a lipoma by imaging characteristics, the unusual extension into the coronary sinus led to consideration of a low-grade liposarcoma in the differential. Thus a pre-operative biopsy was performed along with MDM2 gene amplification to rule out a liposarcoma preceding surgical excision; CONCLUSION: Cardiac lipomas are well-characterized on cardiac MRI, which is the diagnostic modality of choice. Typical locations are the right atrium and the left ventricle. However, in those with atypical features such as invasion of the coronary sinus, pre-operative biopsy for histopathologic confirmation is imperative to exclude well-differentiated liposarcoma. Our patient with a simple lipoma underwent partial resection to relieve symptoms. We discuss prognosis and treatment of symptomatic cardiac lipomas
UR  - https://dx.doi.org/10.1186/s12872-016-0465-2
ER  -