Toxicity of abortifacients: A review for physicians in the post roe era. [Review] 

 -  2022 
<br/><br/> BACKGROUND: On June 24, 2022, the Supreme Court overturned Roe v. Wade, which will limit legal abortion in many areas of the U.S. Over half of abortions in the U.S. are performed using medication as opposed to surgical techniques. With widespread access to agents that are used for medication abortion, there may be an increase in emergency department presentations related to improper or unsupervised use of these medications.  CONCLUSION: Agents used for medication abortion have unique contraindications and adverse effects. Improper or unsupervised use may occur in the setting of limited abortion access and emergency medicine physicians are on the front lines in managing these presentations. Copyright © 2022 Elsevier Inc. All rights reserved.  METHODS: This narrative review focuses on the contraindications, adverse effects, and toxicities of the most common agents used for medication abortion in the U.S.  RESULTS: Medications included in this review are mifepristone, misoprostol, and methotrexate. Each of these medications has a unique adverse effect and toxicity profile. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>0735-6757 
<br/><br/><label>Standard No.: </label>10.1016/j.ajem.2022.08.027 [doi] S0735-6757(22)00528-9 [pii] 
<br/><br/><label>Subjects--Topical Terms: </label><br/>IN PROCESS -- NOT YET INDEXED
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar Washington Hospital Center
<br/><br/><label>Index Terms--Occupation: </label><br/>Emergency Medicine<br/>Obstetrics and Gynecology/Family Planning
<br/><br/><label>Index Terms--Function: </label><br/>Journal Article<br/>Review