Implications of Clostridium septicum in vascular surgery: a case report and outcomes literature review. 

 -  2017 
<br/><br/>Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007 
<br/><br/> Clostridium septicum is a rare organism, accounting for approximately 1.3% of clostridial infections and is associated with synchronous colonic malignancy. This case report describes a patient successfully treated for a mycotic aortic aneurysm secondary to C. septicum bacteremia. Subsequent evaluation confirmed a colonic malignancy, prompting early intervention. A systematic literature review revealing a rate of gastrointestinal malignancy in this patient population is 71%, hematologic malignancy is 3.9%, with the remaining cohort of patients having an unknown source. Infectious involvement of the aorta and associated vascular structures portends a poor prognosis with a 57% mortality rate. Our case and updated review demonstrates the implications of C. septicum vascular seeding and subsequent treatment outcomes.  Copyright (C) 2017 Elsevier Inc. All rights reserved. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>0890-5096 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*Adenocarcinoma/mi [Microbiology]<br/>*Aneurysm, Infected/su [Surgery]<br/>*Aortic Aneurysm, Abdominal/su [Surgery]<br/>*Blood Vessel Prosthesis Implantation<br/>*Clostridium Infections/su [Surgery]<br/>*Clostridium septicum/ip [Isolation & Purification]<br/>*Colonic Neoplasms/mi [Microbiology]<br/>Adenocarcinoma/dg [Diagnostic Imaging]<br/>Adenocarcinoma/su [Surgery]<br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Aneurysm, Infected/dg [Diagnostic Imaging]<br/>Aneurysm, Infected/mi [Microbiology]<br/>Anti-Bacterial Agents/tu [Therapeutic Use]<br/>Aortic Aneurysm, Abdominal/dg [Diagnostic Imaging]<br/>Aortic Aneurysm, Abdominal/mi [Microbiology]<br/>Aortography/mt [Methods]<br/>Biopsy<br/>Clostridium Infections/dg [Diagnostic Imaging]<br/>Clostridium Infections/mi [Microbiology]<br/>Colectomy<br/>Colonic Neoplasms/dg [Diagnostic Imaging]<br/>Colonic Neoplasms/su [Surgery]<br/>Colonoscopy<br/>Computed Tomography Angiography<br/>Early Detection of Cancer/mt [Methods]<br/>Female<br/>Humans<br/>Male<br/>Middle Aged<br/>Treatment Outcome
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar Washington Hospital Center
<br/><br/><label>Index Terms--Occupation: </label><br/>Surgery
<br/><br/><label>Index Terms--Function: </label><br/>Journal Article