TY - BOOK AU - Alimi, Yewande AU - Sosin, Michael TI - Implications of Clostridium septicum in vascular surgery: a case report and outcomes literature review SN - 0890-5096 PY - 2017/// KW - *Adenocarcinoma/mi [Microbiology] KW - *Aneurysm, Infected/su [Surgery] KW - *Aortic Aneurysm, Abdominal/su [Surgery] KW - *Blood Vessel Prosthesis Implantation KW - *Clostridium Infections/su [Surgery] KW - *Clostridium septicum/ip [Isolation & Purification] KW - *Colonic Neoplasms/mi [Microbiology] KW - Adenocarcinoma/dg [Diagnostic Imaging] KW - Adenocarcinoma/su [Surgery] KW - Adult KW - Aged KW - Aged, 80 and over KW - Aneurysm, Infected/dg [Diagnostic Imaging] KW - Aneurysm, Infected/mi [Microbiology] KW - Anti-Bacterial Agents/tu [Therapeutic Use] KW - Aortic Aneurysm, Abdominal/dg [Diagnostic Imaging] KW - Aortic Aneurysm, Abdominal/mi [Microbiology] KW - Aortography/mt [Methods] KW - Biopsy KW - Clostridium Infections/dg [Diagnostic Imaging] KW - Clostridium Infections/mi [Microbiology] KW - Colectomy KW - Colonic Neoplasms/dg [Diagnostic Imaging] KW - Colonic Neoplasms/su [Surgery] KW - Colonoscopy KW - Computed Tomography Angiography KW - Early Detection of Cancer/mt [Methods] KW - Female KW - Humans KW - Male KW - Middle Aged KW - Treatment Outcome KW - MedStar Washington Hospital Center KW - Surgery KW - Journal Article N1 - Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007 N2 - Clostridium septicum is a rare organism, accounting for approximately 1.3% of clostridial infections and is associated with synchronous colonic malignancy. This case report describes a patient successfully treated for a mycotic aortic aneurysm secondary to C. septicum bacteremia. Subsequent evaluation confirmed a colonic malignancy, prompting early intervention. A systematic literature review revealing a rate of gastrointestinal malignancy in this patient population is 71%, hematologic malignancy is 3.9%, with the remaining cohort of patients having an unknown source. Infectious involvement of the aorta and associated vascular structures portends a poor prognosis with a 57% mortality rate. Our case and updated review demonstrates the implications of C. septicum vascular seeding and subsequent treatment outcomes; Copyright (C) 2017 Elsevier Inc. All rights reserved UR - https://dx.doi.org/10.1016/j.avsg.2017.03.178 ER -